PMID: 9181642Jan 1, 1997Paper

Hepatitis A immunity in the Swedish population. A study of the prevalence of markers in the Swedish population

Scandinavian Journal of Infectious Diseases
M BöttigerL Grillner

Abstract

After a 20-year interval, the prevalence of seroimmunity to Hepatitis A (HA) was again investigated in a statistical sample of the adult Swedish population. Sera from 3382 of the 4800 originally selected persons were tested. The prevalence of antibodies to HA had not changed since the 1960s when only the Scandinavian population was considered. In the oldest population born at the beginning of this century, the presence of antibodies amounted to 69%. It gradually declined to 6% in those born in the 1940s. In the population born after 1950, the percentage of seropositive individuals was only 2%. A slightly higher prevalence was seen in the big cities, compared with the rural areas (13% vs 9%). Persons of non-Scandinavian origin showed a different pattern. Those from other European countries showed a prevalence of about 70% in all the age-groups investigated. Among the young adults of Arabic or Asiatic origin, the figure was > 90%. The conclusion is that the native Swedish population has a low natural exposure to HA, which has not changed during the last 20 years. Prophylaxis before going to countries where the disease is endemic is strongly recommended.

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Citations

Jan 27, 1998·Journal of Medical Virology·S P SylvanB Christenson
May 10, 2002·Journal of Gastroenterology and Hepatology·Yong PoovorawanVoranush Chongsrisawat
Sep 11, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peer B ChristensenRobert H Purcell
Jan 9, 2001·Clinical Microbiology Reviews·J A Cuthbert
Jul 9, 2005·BMC Infectious Diseases·Ba' PhamDavid W Scheifele
Jun 1, 1997·Japanese Journal of Medical Science & Biology·T KiyoharaY Moritsugu
Apr 27, 2010·Journal of Medical Virology·Mia BromanIrja Davidkin
Aug 13, 1999·The American Journal of Gastroenterology·T FujisawaY Matsunaga
Nov 6, 2007·European Journal of Epidemiology·Filippo AnsaldiUNKNOWN Serologic Study Group
Aug 16, 2005·Scandinavian Journal of Infectious Diseases·David FitzsimonsPierre van Damme
Apr 16, 2005·International Journal of Epidemiology·K H Jacobsen, J S Koopman
Oct 18, 2005·Journal of Travel Medicine·Christine Luxemburger, Anil K Dutta
Dec 17, 2020·Human Vaccines & Immunotherapeutics·Christian HerzogPierre Van Damme

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