Hepatitis A virus immunity and vaccination among at-risk persons receiving HIV medical care

Preventive Medicine Reports
Nicholas P DeGrooteJohn Weiser

Abstract

United States guidelines recommend hepatitis A virus (HAV) vaccination for persons living with HIV (PLWH) who are at increased risk for HAV infection, including men who have sex with men (MSM) and persons who inject drugs (PWID). However, nationally representative estimates of vaccine coverage and immunity for this population are lacking. We used medical record and interview data from the 2009-2012 cycles of the Medical Monitoring Project, a nationally representative surveillance system of PLWH receiving HIV medical care in the United States, to estimate the prevalence of HAV immunity, defined as receipt of at least one dose of vaccine or laboratory documentation of anti-HAV antibodies, among 8695 MSM and PWID. Among HAV-nonimmune PLWH, we then examined factors associated with HAV vaccination during the 12-month retrospective observation period using Rao-Scott chi-square tests. Among MSM and PWID receiving HIV medical care, 64% had evidence of HAV immunity. Among those who were nonimmune, 10% were vaccinated during the 12-month retrospective observation period. Factors associated with vaccination during follow-up included younger age (i.e., 18-29 years), self-reported black non-Hispanic race/ethnicity, having detectable HIV RNA...Continue Reading

Citations

Jan 8, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Sung-Hsi HuangUNKNOWN Taiwan HIV Study Group
Nov 14, 2019·Journal of Community Health·Alwyn CohallCaroline Carnevale
Jul 3, 2020·MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports·Noele P NelsonAaron M Harris
Jun 23, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·John K WeiserR Luke Shouse
Feb 10, 2020·Clinical Journal of Gastroenterology·Yukihiro YoshimuraNatsuo Tachikawa

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