PMID: 7992329Sep 1, 1994Paper

Hepatitis B and C in Juba, southern Sudan: results of a serosurvey

Transactions of the Royal Society of Tropical Medicine and Hygiene
M C McCarthyK C Hyams

Abstract

To compare the epidemiology of hepatitis B virus (HBV) with hepatitis C virus (HCV) in a southern Sudanese population, 666 out-patients attending 6 public clinics in the city of Juba were enrolled in a serosurvey. The average age of subjects was 16 years; 54% were female. Of the 651 samples tested for hepatitis B markers, HBsAg was found in 26% and anti-HBc in 67%. In contrast, only 21 (3%) of the 666 samples were positive for anti-HCV using a second generation immunoblot assay (RIBA-2). Seventeen (81%) of the 21 anti-HCV-positive subjects were positive for anti-HBc, compared to 66% (418/630) of subjects negative for anti-HCV (P = 0.07). None of the anti-HCV-positive subjects reported receiving a prior blood transfusion and only 5 subjects reported a history of jaundice. Nine of the 21 (43%) anti-HCV-positive subjects reported a history of scarification, compared to 23% (148/645) of anti-HCV-negative subjects (P = 0.01). Hepatitis B infection was also associated with scarification by univariate analysis. However, after adjustment for age a history of scarification was not significantly associated with hepatitis C infection, but it was with HBV infection (odds ratio = 1.5, 95% CI 1.0-2.5; P = 0.05). The findings of this study in...Continue Reading

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Jan 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·D M WattsK C Hyams

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Citations

Jan 4, 2001·Microbes and Infection·S BellentaniC Tiribelli
Oct 26, 2007·Virology Journal·Rasha M ElsheikhIshag Adam
Sep 25, 2009·Virology Journal·Mustafa Abdalla Ali AbouAbdelwahid Saeed Ali
Jan 1, 2008·Clinical and Experimental Gastroenterology·Hatim My Mudawi
Jun 14, 2002·The Lancet Infectious Diseases·Valsa MadhavaErnest Drucker
Sep 17, 2015·Pediatric Blood & Cancer·Mohammed Abdalla, Tarig Hamad
Mar 21, 2001·The Journal of General Virology·P Simmonds
Dec 3, 2014·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Mukhlid YousifAnna Kramvis
May 18, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hari ShankarPonni V Perumalswami
Apr 6, 2017·Tropical Medicine & International Health : TM & IH·Roland GarveChristian G Meyer
Jul 14, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Anna Kramvis, Michael C Kew
Feb 22, 2007·Journal of Medical Virology·Hatim M Y MudawiSuleiman S Fedail
Nov 18, 2015·World Journal of Gastroenterology : WJG·Rosa ZampinoNicola Coppola

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