Hepatitis B and C

Pediatric Clinics of North America
Wikrom Karnsakul, Kathleen B Schwarz

Abstract

Chronic viral hepatitis is a global health threat and financial burden. Hepatitis B and C viruses (HBV and HCV) are the most common causes of chronic viral hepatitis in the United States. Most cases are asymptomatic before adulthood. Research has resulted in effective therapy for HCV and the promise of effective therapies for HBV. For HCV, therapy is pegylated interferon and ribavirin. Clinical trials with effective direct-acting antiviral agents are underway in pediatrics. For HBV, approved agents are alpha-interferon, lamivudine, adefovir, tenofovir, and entecavir. However, treatment seldom results in functional cure and more effective therapies are urgently needed.

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Citations

Oct 20, 2018·Minerva pediatrica·Irini D BatsisWikrom W Karnsakul
Aug 18, 2018·BMJ Global Health·Adriana Velazquez BerumenSoumya Swaminathan
Jul 23, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Shina Menon, Raj Munshi
Jul 3, 2018·World Journal of Gastroenterology : WJG·Malgorzata PawlowskaKrzysztof Domagalski
Apr 14, 2019·Journal of Viral Hepatitis·Wikrom Karnsakul, Kathleen B Schwarz
Oct 6, 2019·Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology·Mortada El-Shabrawi, Fetouh Hassanin
Apr 24, 2020·Journal of Clinical Gastroenterology·Sammy SaabPrabhu Gounder
Mar 17, 2020·Clinics and Research in Hepatology and Gastroenterology·Maria Grazia ClementePietro Vajro
Jul 7, 2021·Cell Biochemistry and Function·Reza RanjbarMortaza Taheri-Anganeh
Nov 2, 2021·Journal of Applied Microbiology·Nathália Alves Araujo de Almeida, Vanessa Salete de Paula
Dec 19, 2019··Tri Nugraha SusilawatiAlfin Titian Permata

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