PMID: 11338062May 8, 2001Paper

Hepatitis B vaccination in liver transplant candidates

European Journal of Gastroenterology & Hepatology
L Castells, R Esteban

Abstract

Liver transplantation has become the treatment of choice for patients with end-stage liver disease. De novo hepatitis B infection after liver transplantation is a rare event and usually runs a mild clinical and histological course. Despite the favourable outcome, a wide spectrum of hepatitis B virus (HBV)-associated liver disease may develop, ranging from asymptomatic carriage to severe chronic active hepatitis or cirrhosis and even fulminant hepatic failure. The achievement of protective titres of anti-HBs through vaccination has been suggested to be protective against the development of de novo HBV infection. The results of vaccination in cirrhotic patients awaiting for liver transplant have been very disappointing. High-dose/short-term schedules have been tried in transplant candidates in order to increase the response rate. New and more immunogenic formulations (containing new adjuvants or additional pre-S1/pre-S2 recombinant antigens), and, more importantly, early vaccination of potential transplant candidates at earlier stages of their liver disease should further prevent de novo hepatitis B in transplant recipients.

References

Aug 1, 1992·Digestive Diseases and Sciences·D H Van ThielT E Starzl
Jun 3, 1989·Lancet·J A Quiroga, V Carreño
Dec 1, 1985·The Journal of Infectious Diseases·M J NowickiR E Bohman
Feb 1, 1988·The Journal of Infectious Diseases·B SeaworthJ Hamilton
Jul 1, 1995·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·R RaultF Bender
Jan 16, 1997·The New England Journal of Medicine·S M Lemon, D L Thomas
Feb 12, 1998·Transplantation·S F DodsonJ J Fung
Mar 28, 1998·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·R FabiaG B Klintmalm
Mar 28, 1998·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·N ChalasaniT D Boyer
May 22, 1998·Transplantation Proceedings·B KallinowskiW Stremmel
Dec 18, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·T PropstP König
May 5, 1999·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·J CrespoF Pons-Romero
Feb 3, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·F RahmanH F Löhr
Jul 29, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·M DomínguezJ Nuño
Aug 12, 2000·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·E VilleneuveJ P Villeneuve
May 8, 2001·European Journal of Gastroenterology & Hepatology·S H EnglerB Kallinowski

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Citations

Oct 3, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Lluís CastellsJaime Guardia
Mar 10, 2009·Medicina clínica·Luis Vida PérezJuan Francisco De Dios Vega
Mar 10, 2009·Medicina clínica·Lluís Castells
May 13, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Chee-kin HuiGeorge K K Lau
Sep 24, 2005·Pediatric Transplantation·Andrew L Campbell, Betsy C Herold
Jun 6, 2009·Transplant International : Official Journal of the European Society for Organ Transplantation·Hiroyuki TaharaHideki Ohdan
Jan 18, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·C-C LinH-L Eng
Aug 19, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Yuji SoejimaYoshihiko Maehara
May 22, 2003·Dermatologic Clinics·Mathijs H BrentjensStephen K Tyring
Sep 27, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Gregory A Poland, John J Poterucha
Aug 19, 2014·World Journal of Gastroenterology : WJG·Martina FilippelliSalvatore Leonardi
Jul 2, 2016·Current Opinion in Pediatrics·Shreena S Patel, Daniel H Leung
Oct 27, 2015·World Journal of Gastroenterology : WJG·Chih-Che LinChao-Long Chen
Nov 14, 2019·Arquivos De Gastroenterologia·Isabela Cristina RodriguesRenato Ferreira da Silva

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