Hepatitis B vaccination strategies tailored to different endemicity levels: some considerations

Vaccine
N Y RotsC J P Boog

Abstract

Hepatitis B is a serious public health problem. Worldwide three different levels of hepatitis B endemicity (high, intermediate and low) can be distinguished. Areas with different levels of endemicity require tailored vaccination strategies to fit the needs for individuals at risk and/or countries, depending on the infection risk per age group, vaccination rate, duration of protection after vaccination, cost effectiveness of vaccination strategies and ease of implementation in the national immunization schedules.This opinion paper evaluates these factors and proposes a combination of infant risk group and universal adolescent vaccination for low endemic countries thus targeting the different groups at risk. A universal infant vaccination schedule starting with a newborn vaccination within 24h after birth is more appropriate in intermediate- and high-endemic regions.

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Citations

Jul 16, 2013·Transactions of the Royal Society of Tropical Medicine and Hygiene·Cristina Masuet-AumatellSandra Lucía Montaño Rodríguez
May 25, 2011·The Pediatric Infectious Disease Journal·Antonella DiamantiGuiliano Torre
Apr 13, 2013·Journal of Travel Medicine·Douglas F JohnsonJoseph Torresi
Sep 9, 2017·Tropical Diseases, Travel Medicine and Vaccines·Kittiyod PoovorawanWatcharapong Piyaphanee

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