Hepatitis B virus contact disclosure and testing in Lusaka, Zambia: a mixed-methods study

BMJ Open
Sarah FranklinMichael J Vinikoor

Abstract

The aim of this study was to estimate the frequency of disclosure to and testing of contacts of patients with hepatitis B virus (HBV) in Zambia. We used a convergent parallel mixed-method research design including a quantitative survey and focus group discussions with patients with HBV. A university hospital in Lusaka, Zambia. 79 hepatitis B surface antigen (HBsAg)-positive, HIV-negative, adults (18+ years) receiving HBV care completed a quantitative survey and 32 also participated in a focus group discussion. Contacts of patients with HBV were enumerated and patient-reported disclosure, contact testing and contact HBV test results were used to develop a testing cascade. Using multivariable logistic regression, we identified factors associated with disclosure of HBV status. In focus groups, we explored how index patient knowledge and awareness of their condition shaped perspectives on contact disclosure and testing. Focus groups coding and analysis followed a thematic analysis approach. Among 79 patients with HBV (median age 35 years; 26.6% women), the majority reported disclosure to ≥1 contact. According to the index patients' knowledge, of 776 contacts enumerated, 326 (42.1%) were disclosed to, 77 (9.9%) were tested, 67 (8.6%...Continue Reading

Associated Clinical Trials

May 18, 2017·Michael Vinikoor

References

Jun 1, 1991·International Journal of Epidemiology·S S Abdool KarimH M Coovadia
Jan 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anna S F Lok, Brian J McMahon
Nov 16, 2010·Bulletin of the World Health Organization·Jane Parry
Jul 13, 2011·Liver International : Official Journal of the International Association for the Study of the Liver·Yu ShiZhi Chen
Jul 16, 2011·The Korean Journal of Hepatology·So Young Kwon, Chang Hong Lee
Aug 24, 2011·Digestive Diseases and Sciences·Ke-Qin HuDiane Goodwin
Dec 14, 2011·PloS One·Tarissa MitchellJohn A Painter
Jul 26, 2012·Seminars in Immunopathology·Giovanni RaimondoTeresa Pollicino
Sep 21, 2012·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·Dorothy LiHemant Shah
May 22, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Jiaxin HuangAnna S Lok
Aug 4, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Brian J McMahon
Oct 23, 2016·Journal of Community Health·Shanna ChengAnna S Lok
Jan 14, 2017·Asia-Pacific Journal of Oncology Nursing·Haeok LeeJin Hyang Yang
Jan 20, 2017·Canadian Journal of Gastroenterology & Hepatology·Lan DamScott J Cotler

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

Dedoose

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.