Hepatitis C among vulnerable populations: A seroprevalence study of homeless, people who inject drugs and prisoners in London

Journal of Viral Hepatitis
D N AisyahAlistair Story

Abstract

Injecting drugs substantially increases the risk of hepatitis C virus (HCV) infection and is common in the homeless and prisoners. Capturing accurate data on disease prevalence within these groups is challenging but is essential to inform strategies to reduce HCV transmission. The aim of this study was to estimate the prevalence of HCV in these populations. We conducted a cross-sectional study between May 2011 and June 2013 in London and, using convenience sampling, recruited participants from hostels for the homeless, drug treatment services and a prison. A questionnaire was administered and blood samples were tested for hepatitis C. We recruited 491 individuals who were homeless (40.7%), 205 drug users (17%) and 511 prisoners (42.3%). Eight per cent of patients (98/1207, 95% CI: 6.7%-9.8%) had active HCV infection and 3% (38/1207, 95% CI: 2.3%-4.3%) past HCV infection. Overall, one quarter (51/205) of people recruited in drug treatment services, 13% (65/491) of people from homeless residential sites and 4% (20/511) prisoners in this study were anti-HCV positive. Seventy-seven of the 136 (56.6%, 95% CI: 47.9%-65%) of HCV infected participants identified had a history of all three risk factors (homelessness, imprisonment and dr...Continue Reading

References

Nov 11, 1999·European Journal of Epidemiology·J R PallásM Delgado-Rodríguez
Feb 8, 2002·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Chiyu ZhangKunlong Ben
Feb 14, 2002·Journal of General Internal Medicine·Adeline M NyamathiLillian Gelberg
Mar 22, 2002·Journal of Clinical Gastroenterology·Ramsey C CheungSuzanne M Matsui
Mar 27, 2002·American Journal of Epidemiology·Lorna E ThorpeRichard S Garfein
Aug 29, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Cari L MillerMartin T Schechter
Nov 26, 2002·The Journal of Infectious Diseases·Judith A HahnAndrew R Moss
May 16, 2003·Seminars in Pediatric Infectious Diseases·Bettina M BeechNita S Kernick
Jan 30, 2004·Journal of Public Health Medicine·Luke C H Sherriff, R T Mayon-White
Jul 1, 2004·Drug and Alcohol Dependence·Judith A Stein, Adeline Nyamathi
Sep 21, 2004·Journal of Gastroenterology and Hepatology·Lisa MaherPenny Sargent
Jan 11, 2005·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Oliver G PybusPeter Simmonds
Nov 3, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rebecca J GartenXiao-Fang Yu
Sep 15, 2007·The International Journal on Drug Policy·Carmen Aceijas, Tim Rhodes
Mar 15, 2008·Journal of Epidemiology and Community Health·M F VescioR Monarca
Jun 29, 2011·European Journal of Public Health·Ross J HarrisDaniela De Angelis
Jan 10, 2013·Addiction·Avril TaylorMatthew Hickman
Mar 19, 2013·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Sarah LarneyLouisa Degenhardt
Apr 12, 2014·The New England Journal of Medicine·Kris V KowdleyUNKNOWN ION-3 Investigators
Apr 15, 2014·The New England Journal of Medicine·Nezam AfdhalUNKNOWN ION-1 Investigators
Aug 13, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anil G SuryaprasadScott D Holmberg
Jan 5, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Tarik AsselahPatrick Marcellin

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Citations

May 30, 2019·Addiction·Alison D MarshallCarla Treloar
Jul 28, 2019·PloS One·Jacob SøholmPeer Brehm Christensen
Jul 5, 2019·International Journal of Environmental Research and Public Health·Biao ZhouYong Di Di Chen
Oct 26, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Jeffrey V LazarusAhmed M Elsharkawy
Jul 25, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Mariano FelisbertoCelso Spada

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