Hepatitis C treatment eligibility and comorbid medical illness in methadone maintenance (MMT) and non-MMT patients: a case-control study.

Journal of Addictive Diseases
Steven L BatkiRobert A Levine

Abstract

Comorbid medical illness is common in patients with chronic hepatitis C (HCV) infection and in methadone treatment (MMT) patients, yet little is known about the impact of medical illness on HCV treatment eligibility. Medical illness and HCV treatment eligibility were compared in a case-control study of 80 MMT patients entering an HCV treatment trial and 80 matched non-MMT patients entering HCV treatment in a gastroenterology clinic. 91% of MMT and 85% of non-MMT patients had chronic medical conditions. Despite similar medical severity ratings, a significantly higher proportion (77%) of non-MMT patients were eligible for HCV treatment than were MMT patients (56%) (p<.01). Specific comorbid medical and psychiatric illness led to ineligibility in only 18% of MMT and 16% of non-MMT patients. However, failure to complete the medical evaluation process was significantly (p<.001) more likely to cause ineligibility among MMT patients (19%) than non-MMT patients (0%).

References

May 1, 1968·Journal of the American Geriatrics Society·B S LinnL Gurel
Jan 1, 1993·Journal of the American Geriatrics Society·Y ConwellE D Caine
Dec 17, 1997·Journal of Clinical Microbiology·S A VillanoD L Thomas
Jul 15, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·R S GarfeinD Vlahov
Aug 18, 2000·Seminars in Liver Disease·P A Sheiner
Jun 30, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M BackmundD Eichenlaub
Jul 21, 2001·The New England Journal of Medicine·B R EdlinB Lo
Jul 21, 2001·The New England Journal of Medicine·G L Davis, J R Rodrigue
Jan 26, 2002·The American Journal of Gastroenterology·Cathey H CawthorneClaus J Fimmel
Feb 19, 2002·Annals of Internal Medicine·Yngve Falck-YtterArthur J McCullough
Jul 4, 2002·Drug and Alcohol Dependence·Diana L Sylvestre
Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·UNKNOWN National Institutes of Health
Nov 26, 2002·The Journal of Infectious Diseases·Judith A HahnAndrew R Moss
Apr 15, 2003·Clinics in Liver Disease·Leonard B Seeff, Jay H Hoofnagle
Feb 10, 2004·The American Journal on Addictions·Israel De AlbaRichard Saitz
May 28, 2004·The New England Journal of Medicine·Andrew J MuirUNKNOWN Atlantic Coast Hepatitis Treatment Group
Nov 20, 2004·The Psychiatric Clinics of North America·William C Wadland, Gary S Ferenchick
Nov 27, 2004·Psychosomatic Medicine·Winfried HäuserDaniel Grandt
May 10, 2005·Journal of Clinical Epidemiology·C HudonA Vanasse
Jul 30, 2005·Journal of General Internal Medicine·James A MorrillRichard W Grant
Aug 27, 2005·The Lancet Infectious Diseases·Colin W ShepardMiriam J Alter
Sep 2, 2005·Pharmacoepidemiology and Drug Safety·C Bradley HareWinslow Klaskala
Oct 18, 2005·Alimentary Pharmacology & Therapeutics·A AlbertiR Pistis
Nov 3, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jag H KhalsaFrancis Vocci
Nov 3, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Diana L Sylvestre
Nov 12, 2005·Substance Use & Misuse·Joy C Draper, Elinore F McCance-Katz
Aug 8, 2006·Gastroenterology·Hari S ConjeevaramUNKNOWN Virahep-C Study Group
Feb 27, 2007·The American Journal of Gastroenterology·Mitchell L ShiffmanArun J Sanyal
Jun 22, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kostas N FountasArthur A Grigorian
Sep 15, 2007·The International Journal on Drug Policy·Holly HaganPeter L Flom
May 9, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph J AmonIan T Williams
Aug 7, 2008·Journal of Addictive Diseases·Jag H Khalsa, Frank Vocci
Dec 2, 2008·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Jag H KhalsaEllen Tedaldi
Dec 17, 2008·Alimentary Pharmacology & Therapeutics·J J WeissG J Wagner

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Citations

Jul 31, 2018·The International Journal of Neuropsychopharmacology·Sheng-Chang WangYu-Li Liu

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Methods Mentioned

BETA
contraception
biopsy
PCR

Clinical Trials Mentioned

NCT00148031

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