Hepatitis C Virus Exposure Rate among Health-care Workers in Rural Lower Egypt Governorates

Journal of Translational Internal Medicine
Ashraf ElbahrawyHafez Abdelhafeez

Abstract

Studies on hepatitis C virus (HCV) in Egypt supported a strong role for various exposures in the health-care setting. In this study, we attempted to estimate the frequency of HCV exposure among Egyptian health-care workers (HCWs). Five hundred and sixty-four (564) HCWs were included in this study. Two hundred and fifty-eight (45.74%) were health-care providers and 306 (54.25%) were non-health-care providers. All HCWs completed both the study questionnaire and provided a blood sample for anti-HCV testing by third-generation enzyme-linked immunosorbent assay. Subsequently, anti-HCV-positive samples were tested for HCV RNA using nested polymerase chain reaction (PCR). The mean age of included HCWs was 33.0 ± 9.8 years; of them, 319 (56.56%) were males and 245 (43.44%) were females. The mean duration of health-care work was 9.3 ± 6.7 years. The frequency of antibody against hepatitis C virus (anti-HCV) among included HCWs was 8.7% (n = 49). Old age and prolonged duration of health-care work were significantly associated with anti-HCV seropositivity. Forty (81.63%) of 49 with anti-HCV-positive HCWs had positive hepatitis C viremia. The frequency of HCV RNA positivity increased with age. The frequency of eradicated past infection amo...Continue Reading

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Citations

Aug 10, 2018·World Journal of Gastroenterology : WJG·Jing-Bo WangHai-Tao Wang
Jun 4, 2021·Environmental Health and Preventive Medicine·Daniel AtlawZerihun Tariku
May 16, 2021·Microbiology and Immunology·Ashraf ElbahrawyHussein Hassan Aly

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