Hepatitis C virus (HCV) infection and hepatic steatosis.

International Journal of Medical Sciences
Eugene J Yoon, Ke-Qin Hu

Abstract

There are two discrete forms of steatosis that may be found in patients infected with hepatitis C virus (HCV). Metabolic steatosis can coexist with HCV, regardless of genotype, in patients with risk factors such as obesity, hyperlipidemia, and insulin resistance. The second form of hepatic steatosis in HCV patients is a result of the direct cytopathic effect of genotype 3 viral infections. There have been proposed mechanisms for this process but it remains elusive. Both categories of steatosis tend to hasten the progression of liver fibrosis and therefore prompt recognition and management should be initiated in patients with HCV and steatosis. The authors review the current understanding of the relationship between hepatitis C infection and hepatic steatosis and discuss future research directions.

References

Nov 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·I R Wanless, J S Lentz
Nov 3, 1994·The New England Journal of Medicine·J J NolanJ Olefsky
Feb 29, 1996·The New England Journal of Medicine·C J Bailey, R C Turner
Feb 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·G BarbaC Bréchot
Sep 25, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A SabileG Barba
Nov 24, 1999·The American Journal of Medicine·G MarchesiniN Melchionda
Jul 25, 2000·Journal of Hepatology·L Rubbia-BrandtF Negro
Feb 24, 2001·Journal of Gastroenterology and Hepatology·S J HwangS D Lee
Apr 3, 2001·Journal of Hepatology·A D CloustonE E Powell
Apr 12, 2001·Seminars in Liver Disease·E M Brunt
Jun 8, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·L E AdinolfiG Ruggiero
Feb 5, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gianfranco PaganoMario Rizzetto
Feb 5, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Shivakumar ChitturiJacob George
Mar 27, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Takeya TsutsumiTatsuo Miyamura
Oct 3, 2002·The American Journal of Gastroenterology·Vicente OrtizJoaquin Berenguer
Apr 2, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Giulio MarchesiniMario Rizzetto
Jun 12, 2003·JAMA : the Journal of the American Medical Association·Jeanne M Clark, Anna Mae Diehl
Sep 27, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Brent A Neuschwander-TetriBruce R Bacon
Sep 11, 2004·Journal of Viral Hepatitis·C HézodeJ-M Pawlotsky
Mar 4, 2005·The American Journal of Gastroenterology·Laurent CasteraJean-Michel Pawlotsky

❮ Previous
Next ❯

Citations

Oct 3, 2012·PloS One·Stephanie TraubLena Alexopoulou
Mar 24, 2009·AJR. American Journal of Roentgenology·Muriel WebbRan Oren
Jul 2, 2009·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Alia ZubairAzhar Mubarik
Feb 9, 2008·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·J de NagyR V Lee
Jun 15, 2017·Expert Review of Gastroenterology & Hepatology·Hassan H A-Kader
Jan 9, 2015·Clinical Pediatrics·Suchitra K HouriganAnn O Scheimann
Nov 6, 2007·Nature Clinical Practice. Gastroenterology & Hepatology·John A MengsholHugo R Rosen
Nov 22, 2007·Journal of Gastroenterology and Hepatology·Chia-Chi WangDing-Shinn Chen
Jul 20, 2010·Journal of Biomolecular Screening·Ross WhittakerPatrick M McDonough
Oct 6, 2011·Archives of Pathology & Laboratory Medicine·Rachel Hudacko, Neil Theise
Aug 21, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Zhongzhou SiJiequn Li
Jul 29, 2006·International Journal of Circumpolar Health·Stephen E LivingstonDavid R Gretch
Jan 5, 2019·Infectious Diseases and Therapy·Berend J van WelzenJoop E Arends

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsies
biopsy

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved