Hepatitis E Virus Infection During Pregnancy: The Overlooked Cause of Maternal and Fetal Mortality

Infectious Disorders Drug Targets
Fatemeh FarshadpourReza Taherkhani

Abstract

Hepatitis E virus (HEV) is one the leading causes of maternal and fetal mortality. Nevertheless, in some geographical locations, especially Egypt, despite having high frequency of HEV seropositivity, HEV infection follows an asymptomatic or mild course during pregnancy. These anomalous observations have distracted attention from the importance of HEV infection in pregnant women. While tragic cases of HEV-infected pregnant women cannot be neglected any longer. These circumstances create a strong demand for the increasing awareness of HEV infection through training programs, appropriate management of HEV infection among pregnant women, routine screening of pregnant women for timely diagnosis of HEV infection, proper treatment of HEVinfected patients, optimal preventive measures, and development of a prophylactic vaccine against HEV infection.

References

Jan 5, 2012·World Journal of Hepatology·Eyasu H Teshale, Dale J Hu
Jan 8, 2014·Clinical Microbiology Reviews·Nassim KamarJacques Izopet
Jun 7, 2014·BMC Infectious Diseases·Jong-Hoon KimThomas F Wierzba
Jul 23, 2015·Hepatitis Research and Treatment·Fatemeh FarshadpourManoochehr Makvandi
Sep 4, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Rashi SehgalNirupama Trehanpati
Jun 15, 2016·World Journal of Gastroenterology : WJG·Reza Taherkhani, Fatemeh Farshadpour
Jun 21, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Jayanta BorkakotiPremashis Kar
Sep 10, 2016·World Journal of Gastroenterology : WJG·Mohammad S KhurooNaira S Khuroo
Apr 1, 2017·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Jayanta BorkakotiPremashis Kar
Apr 13, 2017·Internal Medicine Journal·Waled Mohsen, Miriam T Levy

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