Hepatoblastoma in a girl with biliary atresia: coincidence or co-incidence

Pediatric Blood & Cancer
F TaatD C Aronson

Abstract

Hepatoblastoma (HB) and biliary atresia (BA) are both rare conditions that occurred in the patient described. This is the second such case in the literature. An explanation for this apparent coincidence could possibly be found in the existance of pluripotent liver stem cells. In humans, small epithelial cells (SEC) behave as pluripotent stem cells. These are cells that can develop as biliary epithelial cells or as liver parenchymal cells, and are thought to be the precursor cell of HB. They are present in a much higher concentration in the livers of patients with BA, which may make them prone to develop HB.

References

May 17, 2000·Journal of Pediatric Surgery·A CarcellerM Di Lorenzo
Feb 28, 2001·Journal of Pediatric Surgery·Y TatekawaK Tanaka
Feb 20, 2003·Journal of Pediatric Surgery·Takaharu OueHiroyuki Kitajima
Aug 27, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anil DarbariKathleen B Schwarz

❮ Previous
Next ❯

Citations

Jan 11, 2013·ISRN Surgery·Barbara E Wildhaber
Nov 1, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Milton J FinegoldChristine Ann O'Mahony
Nov 23, 2005·Cell Proliferation·M R Alison, M J Lovell
Jul 28, 2016·Journal of Pediatric Gastroenterology and Nutrition·Achiya Z AmirVicky L Ng
Feb 9, 2018·Journal of Pediatric Hematology/oncology·Julie BennettFurqan Shaikh
Sep 25, 2019·Cancers·Nirmala Mavila, Jyothi Thundimadathil

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
Henning C FiegelDietrich Kluth
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
D ThomasJean de Ville de Goyet
© 2021 Meta ULC. All rights reserved