Abstract
Despite a rise in the prevalence of hepatocellular carcinoma (HCC), data on HCC-related hospitalizations and financial burden are limited. The aim of this study was to evaluate temporal trends of HCC-related hospitalizations and evaluate its financial influence. Patients with the diagnosis of HCC, as reported by International Classification of Diseases-Ninth Revision code, were identified from the National Inpatient Sample databases from 2002-2011. The national estimates of hospitalizations were derived using appropriate sample weights. The change in total average charges per each hospitalization over the study period was calculated after adjusting for inflation. Hospitalizations related to HCC have increased from 24,024 in 2002 to 50,609 in 2011. Of these admissions, HCC was the principal diagnosis in 10,762 and 16,350 subjects in 2002 and 2011, respectively. Most were white males (male: 70%; white: 55%). The overall inpatient mortality was significantly decreased from 13.5% in 2002 to 9.9% in 2011 (P < 0.01). The same trend was also observed for the length of hospital stay (6.5 versus 5.6 days in 2002 and 2011, respectively). The inflation-adjusted cost per hospitalization increased by approximately 47% during the study perio...Continue Reading
References
Feb 3, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M F YuenC L Lai
Nov 19, 2003·Annals of Internal Medicine·Hashem B El-SeragKatherine A McGlynn
Dec 5, 2006·Annals of Epidemiology·Eric B LoucksIchiro Kawachi
Jul 13, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Geoffrey C NguyenPaul J Thuluvath
Feb 20, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sean F AltekruseMarsha E Reichman
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
Sep 21, 2011·The American Journal of Gastroenterology·Michael L VolkAnna S Lok
Oct 14, 2011·The New England Journal of Medicine·Hashem B El-Serag
Feb 23, 2012·Lancet·Alejandro FornerJordi Bruix
Apr 28, 2012·Gastroenterology·Hashem B El-Serag
Aug 1, 2012·Seminars in Oncology·Cristina Della Corte, Massimo Colombo
Jan 10, 2013·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hla-Hla TheinCraig C Earle
Nov 26, 2013·The Medical Clinics of North America·Reena Salgia, Amit G Singal
Nov 13, 2015·Childhood Obesity·Robert RogersKim A Eagle
Citations
Mar 6, 2019·Digestive Diseases and Sciences·Mehmet SayinerZobair M Younossi
Oct 2, 2019·PharmacoEconomics·Alisa Likhitsup, Neehar D Parikh
Sep 19, 2019·BioMed Research International·Xu LiJunqi Niu
Aug 30, 2019·DNA and Cell Biology·Wenbiao ChenHongyan Diao
Aug 14, 2020·PloS One·Haruhisa FukudaHaku Ishida
Jan 5, 2019·Infectious Diseases and Therapy·Rachel M MurdockMelissa E Badowski
Jun 6, 2019·Journal of Clinical Medicine·Michał GrątKrzysztof Zieniewicz
Apr 1, 2020·Gut Microbes·Vishal SinghMatam Vijay-Kumar
Jul 31, 2020·Expert Review of Gastroenterology & Hepatology·Amir SultanJose D Debes
Aug 11, 2020·Hepatic Oncology·Abdalla AlyFernando Benavente
Jun 23, 2018·Frontiers in Physiology·Xue-Feng LiYu-Ming Niu
Jun 13, 2019·Journal of Cancer Epidemiology·Yasir Al-AzzawiGraham Barnard
Aug 14, 2020·World Journal of Surgical Oncology·Shan JinChunshan Luo
Sep 18, 2020·Annals of Hepatology·Kunichika MatsumotoTomonori Hasegawa
Jan 13, 2021·Digestive Diseases and Sciences·Rui XuXuebing Ji
Nov 9, 2020·Journal of Vascular and Interventional Radiology : JVIR·Xiao WuNishita Kothary
Oct 17, 2020·OncoTargets and Therapy·Yi LiuJianbo Zhou
Jan 24, 2021·Journal of the American College of Radiology : JACR·Xiao WuAjay Malhotra
Mar 23, 2021·Journal of Clinical and Experimental Hepatology·Joseph J AlukalPaul J Thuluvath
Aug 11, 2019·Transplantation Proceedings·Nicholas J SkillMary A Maluccio
Mar 31, 2021·The Journal of Gene Medicine·Jianzhuang GongHuili Wu
May 3, 2021·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Anh Le Tuan NguyenBarbara de Graaff
Jul 22, 2021·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Takeshi TerashimaShuichi Kaneko
Jul 6, 2021·Pharmacology Research & Perspectives·Peng LiLieting Ma
Aug 20, 2021·Hepatic Oncology·Abdalla AlyBrian Seal