Abstract
To investigate whether pre-operative gadoxetic acid-enhanced MRI can predict early recurrence after curative resection of single HCC using image features and texture analysis. 179 patients with single HCC and who underwent pre-operative MRI were included. Two reviewers analyzed MR findings, including the tumor margin, peritumoral enhancement, peritumoral hypointensity on the hepatobiliary phase (HBP), diffusion restriction, capsule, tumoral fat, washout, portal-vein thrombus, signal intensity on HBP, and satellite nodule. Texture analysis on the HBP was also quantified. A multivariate analysis was used to identify predictive factors for early recurrence, microvascular invasion (MVI), and the tumor grade. For early recurrence, satellite nodule, peritumoral hypointensity, absence of capsule, and GLCM ASM were predictors (P < 0.05). For MVI, satellite nodule, peritumoral hypointensity, washout, and sphericity were predictors (P < 0.05). Satellite nodules, peritumoral hypointensity, diffusion restriction, and iso to high signal intensity on HBP were predictor for higher tumor grade (P < 0.05). Satellite nodules and peritumoral hypointensity were important showed common predictors for early recurrence, MVI, and grade (P < 0.05). The...Continue Reading
References
Jan 5, 2002·The American Journal of Surgical Pathology·Gregory Y LauwersUNKNOWN International Cooperative Study Group on Hepatocellular Carcinoma
Mar 29, 2002·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Byung Ihn ChoiJeong Min Lee
May 1, 1954·Cancer·H A EDMONDSON, P E STEINER
Feb 6, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Aurélie PlessierFrançois Durand
Aug 18, 2004·Genes & Development·Deirdre A NelsonEileen White
Jan 25, 2006·Annals of Surgery·Nazario PortolaniStefano Maria Giulini
May 9, 2006·Academic Radiology·Yu-Len HuangWu-Chung Shen
Mar 14, 2007·Surgery·Shimul A ShahSteven Gallinger
Aug 21, 2007·Academic Radiology·Balaji GaneshanChris R Chatwin
Nov 16, 2007·Annals of Surgical Oncology·Gi-Hong ChoiByong-Ro Kim
Feb 5, 2008·European Journal of Radiology·Balaji GaneshanChris R Chatwin
Mar 8, 2008·Annals of Surgical Oncology·Shuji SumieMichio Sata
Sep 26, 2008·The Korean Journal of Hepatology·Ui Jun ParkTae Jin Lim
Dec 20, 2008·Radiology·Kousei IshigamiHiroshi Honda
Jan 24, 2009·Radiology·Kenneth A MilesChristopher R Chatwin
Feb 28, 2009·European Radiology·Honsoul KimKi Whang Kim
Jun 16, 2009·Gastroenterology·Sasan RoayaieMyron E Schwartz
May 27, 2010·Radiology·Takahiro TsuboyamaKaname Tomoda
Jul 29, 2010·Radiology·Azusa KitaoYasuni Nakanuma
Mar 2, 2011·Journal of Hepato-biliary-pancreatic Sciences·Shun-ichi AriizumiMasakazu Yamamoto
Mar 10, 2011·The British Journal of Radiology·N GriffinD J Lomas
Sep 29, 2011·Clinical Radiology·B GaneshanK Miles
Nov 10, 2011·Journal of Magnetic Resonance Imaging : JMRI·Kyung Ah KimYoung Eun Chung
Nov 17, 2011·European Radiology·Balaji GaneshanKen Miles
May 12, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Sasan RoayaieVincenzo Mazzaferro
Jun 16, 2012·World Journal of Surgical Oncology·Toshiya KamiyamaAkinobu Taketomi
Jul 7, 2012·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Young Joo SuhKi Whang Kim
Sep 11, 2012·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Charing Ching-Ning ChongPaul Bo-San Lai
Nov 12, 2015·International Journal of Biomedical Imaging·Nourhan Zayed, Heba A Elnemr
Sep 15, 2016·Journal of Magnetic Resonance Imaging : JMRI·Wu ZhouChanghong Liang
Jan 6, 2017·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Jun 18, 2017·Hepatology International·Masao OmataShiv Kumar Sarin
Citations
Jul 12, 2019·Abdominal Radiology·Fei ZhuWeilin Yang
Jan 17, 2020·Journal of Magnetic Resonance Imaging : JMRI·Shu-Wen SunXi-Sheng Liu
Oct 2, 2020·European Radiology·Hong WeiBin Song
May 16, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Zhen ZhangBin Song
Oct 28, 2019·Radiologia brasileira·Daniel Lahan-MartinsElaine Cristina de Ataide
Jun 26, 2020·Cancer Management and Research·Tao ZhangXiuwen Chen
Apr 9, 2020·Frontiers in Oncology·Yi DongWen-Ping Wang
Jan 12, 2020·Abdominal Radiology·Sara LewisBachir Taouli
Oct 14, 2020·Abdominal Radiology·Xiangmei QiaoKefeng Zhou
Sep 26, 2020·Journal of Computer Assisted Tomography·Jeong Min ChoiJae-Joon Chung
Nov 20, 2020·European Radiology·Jae Seok BaeJoon Koo Han
Jan 26, 2021·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Shingo ShimadaAkinobu Taketomi
Jan 16, 2021·European Radiology·Huan-Huan ChongMeng-Su Zeng
Oct 7, 2020·European Journal of Radiology·Hong WeiBin Song
Oct 30, 2020·European Journal of Radiology·Xinxin WangYang Zhou
May 15, 2021·The British Journal of Radiology·Roberto CannellaMarco Dioguardi Burgio
Jun 8, 2021·Frontiers in Oncology·Chengguang HuYuanping Zhou
Jul 8, 2021·Medicine·Joonho JeongJong Hyouk Yun
Aug 15, 2021·Alimentary Pharmacology & Therapeutics·Emily Harding-TheobaldNeehar D Parikh
Aug 31, 2021·Acta Radiologica·Yuhui DengZhenghan Yang
Apr 2, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Gregory C WilsonAllan Tsung
Nov 20, 2021·The British Journal of Radiology·Hui HuangLi-Da Chen