Hepatocellular carcinoma: preoperative gadoxetic acid-enhanced MR imaging can predict early recurrence after curative resection using image features and texture analysis

Abdominal Radiology
Su Joa AhnJoon Koo Han

Abstract

To investigate whether pre-operative gadoxetic acid-enhanced MRI can predict early recurrence after curative resection of single HCC using image features and texture analysis. 179 patients with single HCC and who underwent pre-operative MRI were included. Two reviewers analyzed MR findings, including the tumor margin, peritumoral enhancement, peritumoral hypointensity on the hepatobiliary phase (HBP), diffusion restriction, capsule, tumoral fat, washout, portal-vein thrombus, signal intensity on HBP, and satellite nodule. Texture analysis on the HBP was also quantified. A multivariate analysis was used to identify predictive factors for early recurrence, microvascular invasion (MVI), and the tumor grade. For early recurrence, satellite nodule, peritumoral hypointensity, absence of capsule, and GLCM ASM were predictors (P < 0.05). For MVI, satellite nodule, peritumoral hypointensity, washout, and sphericity were predictors (P < 0.05). Satellite nodules, peritumoral hypointensity, diffusion restriction, and iso to high signal intensity on HBP were predictor for higher tumor grade (P < 0.05). Satellite nodules and peritumoral hypointensity were important showed common predictors for early recurrence, MVI, and grade (P < 0.05). The...Continue Reading

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Citations

May 16, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Zhen ZhangBin Song
Oct 28, 2019·Radiologia brasileira·Daniel Lahan-MartinsElaine Cristina de Ataide
Jun 26, 2020·Cancer Management and Research·Tao ZhangXiuwen Chen
Jan 12, 2020·Abdominal Radiology·Sara LewisBachir Taouli
Jan 26, 2021·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Shingo ShimadaAkinobu Taketomi
May 15, 2021·The British Journal of Radiology·Roberto CannellaMarco Dioguardi Burgio
Aug 15, 2021·Alimentary Pharmacology & Therapeutics·Emily Harding-TheobaldNeehar D Parikh
Apr 2, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Gregory C WilsonAllan Tsung

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