Hepatocellular carcinoma presenting as a precocious cutaneous metastasis

The American Journal of Dermatopathology
Michael C RoyerGeorge P Lupton

Abstract

The authors report a case of hepatocellular carcinoma (HCC) diagnosed by evaluation of a cutaneous metastasis in a patient without a prior diagnosis of HCC. Subsequent evaluation confirmed the presence of additional widespread metastatic disease. The medical literature is reviewed with regards to cutaneous metastasis, including precocious metastasis, of HCC. The pathologic evaluation of HCC is reviewed, including a discussion of the immunohistochemical profile of this malignancy and the utility of hepatocyte paraffin 1, CD10, and polyclonal carcinoembryonic antigen (pCEA) immunohistochemical stains.

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Citations

Jan 7, 2010·The American Journal of Dermatopathology·Angel Fernandez-Flores
Dec 1, 2011·International Journal of Dermatology·Jenny A MandellKaren J Haglof
Sep 25, 2012·Scottish Medical Journal·M S RaufC Connolly
Jan 21, 2012·The American Journal of Dermatopathology·Joshua A GrossSarah K Barksdale
Nov 6, 2013·Psychonomic Bulletin & Review·Christopher R MadanMarcia L Spetch
Aug 31, 2019·Dermatologic Clinics·Evan Alexander ChoateScott Worswick

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