Abstract
The authors report a case of hepatocellular carcinoma (HCC) diagnosed by evaluation of a cutaneous metastasis in a patient without a prior diagnosis of HCC. Subsequent evaluation confirmed the presence of additional widespread metastatic disease. The medical literature is reviewed with regards to cutaneous metastasis, including precocious metastasis, of HCC. The pathologic evaluation of HCC is reviewed, including a discussion of the immunohistochemical profile of this malignancy and the utility of hepatocyte paraffin 1, CD10, and polyclonal carcinoembryonic antigen (pCEA) immunohistochemical stains.
References
Jan 1, 1990·Journal of the American Academy of Dermatology·D P LookingbillF M Sexton
Jun 1, 1972·Archives of Dermatology·M H Brownstein, E B Helwig
Aug 1, 1993·Journal of the American Academy of Dermatology·D P LookingbillK F Helm
Jul 1, 1996·Journal of Periodontology·F LlanesJ Sanz-Esponera
May 8, 1999·Clinical and Experimental Dermatology·Y KubotaJ Nakayama
Mar 30, 2000·Urologia Internationalis·L N DorairajanN P Gupta
Jul 28, 2001·European Journal of Gastroenterology & Hepatology·H J Hodkinson, M C Kew
Mar 13, 2003·Southern Medical Journal·Richard A KrathenTed Rosen
Jan 28, 2004·Journal of Cutaneous Pathology·J KanitakisJ Y Scoazec
Mar 11, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Mei-Ching LeeHong-Shang Hong
Jun 10, 2004·Digestive Diseases and Sciences·Engin AltintasOzlem Aydin
Aug 24, 2004·Advances in Anatomic Pathology·Vijay Varma, Cynthia Cohen
Dec 3, 2004·BMC Cancer·Sahin CobanAbdulkadir Dökmeci
Oct 26, 2005·Journal of Gastroenterology and Hepatology·Mitsuteru NatsuizakaMasahiro Asaka
Nov 11, 2005·Applied Immunohistochemistry & Molecular Morphology : AIMM·Chin-Chen PanDonald Ming-Tak Ho
Apr 13, 2006·World Journal of Gastroenterology : WJG·Yil-Sik HyunMoon-Hyang Park
Aug 26, 2006·Applied Immunohistochemistry & Molecular Morphology : AIMM·Aileen Wee
Apr 12, 2007·Acta Cytologica·Pedro de AgustínFernando López-Ríos
Citations
Jan 7, 2010·The American Journal of Dermatopathology·Angel Fernandez-Flores
Jun 1, 2012·World Journal of Surgical Oncology·L ZachauH Schrem
Mar 17, 2012·Actas dermo-sifiliográficas·J Alonso-GonzálezJ Toribio
Dec 1, 2011·International Journal of Dermatology·Jenny A MandellKaren J Haglof
Sep 25, 2012·Scottish Medical Journal·M S RaufC Connolly
Jan 21, 2012·The American Journal of Dermatopathology·Joshua A GrossSarah K Barksdale
Nov 6, 2013·Psychonomic Bulletin & Review·Christopher R MadanMarcia L Spetch
Aug 31, 2019·Dermatologic Clinics·Evan Alexander ChoateScott Worswick