Hepatocellular Carcinoma Surveillance Among Cirrhotic Patients With Commercial Health Insurance

Journal of Clinical Gastroenterology
D S GoldbergJ D Lewis

Abstract

To evaluate hepatocellular carcinoma (HCC) surveillance rates among commercially insured patients, and evaluate factors associated with compliance with surveillance recommendations. Most HCC occurs in patients with cirrhosis. American Association for the Study of Liver Diseases and European Association for the Study of the Liver guidelines each recommend biannual HCC surveillance for cirrhotic patients to diagnose HCC at an early, curable stage. However, compliance with these guidelines in commercially insured patients is unknown. We used the Truven Health Analytics databases from 2006 to 2010, using January 1, 2006 as the anchor date for evaluating outcomes. The primary outcome was continuous surveillance measure, defined as the proportion of time "up-to-date" with surveillance (PTUDS), with the 6-month interval immediately following each ultrasound categorized as "up-to-date." During a median follow-up of 22.9 (interquartile range, 16.3 to 33.9) months among 8916 cirrhotic patients, the mean PTUDS was 0.34 (SD, 0.29), and the median was 0.31 (interquartile range, 0.03 to 0.52). These values increased only modestly with inclusion of serum alpha-fetoprotein testing, contrast-enhanced abdominal computed tomographic scans or magn...Continue Reading

References

Jun 1, 1992·Journal of Clinical Epidemiology·R A DeyoM A Ciol
Oct 27, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jordi BruixUNKNOWN Practice Guidelines Committee, American Association for the Study of Liver Diseases
Aug 19, 2007·Journal of Clinical Gastroenterology·Jessica A DavilaHashem B El-Serag
Oct 31, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Michael L VolkJorge A Marrero
Jun 10, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Peter JepsenHenrik Toft Sørensen
Dec 24, 2008·Digestive Diseases and Sciences·Judith I TsuiRalph Gonzales
Feb 10, 2009·Annals of Emergency Medicine·Brendan G CarrCarlos A Camargo
Jan 16, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Guadalupe Garcia-TsaoMassimo Pinzani
Feb 23, 2010·Seminars in Liver Disease·Morris Sherman
Jun 25, 2010·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Morris Sherman
Jun 26, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jessica A DavilaHashem B El-Serag
Jul 17, 2010·Oncology·Morris Sherman
Jan 5, 2011·Transplantation·Heidi YehJames F Markmann
Mar 5, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jordi BruixUNKNOWN American Association for the Study of Liver Diseases
May 4, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Tania M WelzelKatherine A McGlynn
Jul 20, 2011·Nature·Lauren Gravitz
Oct 14, 2011·The New England Journal of Medicine·Hashem B El-Serag
Feb 23, 2012·Lancet·Alejandro FornerJordi Bruix
Mar 20, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·UNKNOWN European Association for Study of Liver, UNKNOWN European Organisation for Research and Treatment of Cancer
Mar 20, 2012·Journal of Hepatology·UNKNOWN European Association For The Study Of The Liver, UNKNOWN European Organisation For Research And Treatment Of Cancer
Oct 24, 2012·Journal of Clinical Gastroenterology·Mahendra S NehraAmit G Singal
Nov 6, 2012·Pharmacoepidemiology and Drug Safety·David S GoldbergVincent Lo Re
Feb 28, 2013·Journal of Clinical Gastroenterology·Lena B PalmerPaul H Hayashi
Jan 24, 2014·Journal of General Internal Medicine·Kenneth J Rothman
Jun 18, 2014·Annals of Internal Medicine·Devan KansagaraJanice H Jou

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Citations

Aug 2, 2016·International Journal of Nursing Practice·Saroj NazarethWendy Cheng
Aug 18, 2016·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·David S GoldbergDavid E Kaplan
Jan 17, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Vincent L ChenNeehar D Parikh
Dec 19, 2016·Hepatology Communications·Neil J MehtaMarion G Peters
May 28, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Eliza W BealCarl R Schmidt
Oct 31, 2017·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Jennifer A CahillKia Saeian
May 28, 2019·Journal of Gastrointestinal Cancer·Winston E AbaraUNKNOWN CHeCS Investigators
May 10, 2020·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Erin WolfAmit G Singal
May 30, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jessica ChubakBeverly B Green
Jan 26, 2021·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Joshua P KronenfeldNeha Goel
Jul 7, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Amit G SingalRuben Hernaez
Nov 29, 2019·Radiology. Imaging Cancer·Ryan L BrunsingClaude B Sirlin
Jul 20, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Briton LeeMa Somsouk

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