Hepatoid adenocarcinoma of the lung metastasizing to the tonsil

Molecular and Clinical Oncology
Luca ValleArun Rajan

Abstract

Hepatoid adenocarcinoma (HAC) is a rare tumor that typically originates in gastrointestinal tissue, such as the stomach, but can also occasionally originate in the lung. The majority of HACs express α-fetoprotein (AFP) on tumor cells, and serum AFP can be used as a marker of response to treatment or disease progression. HAC has a poor prognosis, although early diagnosis and aggressive treatment can result in long-term survival. To the best of our knowledge, this is the first reported case of HAC metastasizing to the tonsil. Irradiation using intensity-modulated radiation therapy (IMRT) to 30 Gray (Gy) achieved a significant, and durable tumor response. IMRT can be considered for local control of HAC at other metastatic sites of disease.

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Citations

Feb 12, 2020·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Onder TonyaliOzlenen Gonca Civi
Apr 30, 2021·Frontiers in Oncology·Ruolan XiaXuelei Ma
Nov 25, 2021·Technology in Cancer Research & Treatment·Meihui LiHongyang Lu

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