Hepatopulmonary syndrome in patients with chronic liver disease: role of pulse oximetry.

BMC Gastroenterology
Peter DeibertHubert Erich Blum

Abstract

Hepatopulmonary syndrome (HPS) is a rare complication of liver diseases of different etiologies and may indicate a poor prognosis. Therefore, a simple non-invasive screening method to detect HPS would be highly desirable. In this study pulse oximetry was evaluated to identify patients with HPS. In 316 consecutive patients with liver cirrhosis (n = 245), chronic hepatitis (n = 69) or non-cirrhotic portal hypertension (n = 2) arterial oxygen saturation (SaO2) was determined using a pulse oximeter. In patients with SaO2 < or = 92% in supine position and/or a decrease of > or = 4% after change from supine to upright position further diagnostic procedures were performed, including contrast-enhanced echocardiography and perfusion lung scan. Seventeen patients (5.4%) had a pathological SaO2. Four patients (1.3%) had HPS. HPS patients had a significant lower mean SaO2 in supine (89.7%, SD 5.4 vs. 96.0%, SD 2.3; p = 0.003) and upright position (84.3%, SD 5.0 vs. 96.0%, SD 2.4; p = 0.001) and had a lower mean PaO2 (56.2 mm Hg, SD 15.2 vs. 71.2 mm Hg, SD 20.2; p = 0.02) as compared to patients without HPS. The mean deltaSaO2 (difference between supine and upright position) was 5.50 (SD 7) in HPS patients compared to non-HPS patients who s...Continue Reading

References

Sep 1, 1977·Chest·T C Kennedy, R J Knudson
Apr 22, 1976·The New England Journal of Medicine·E D RobinJ Theodore
Nov 1, 1992·Thorax·R Rodríguez-RoisinJ Roca
Aug 15, 1992·The American Journal of Cardiology·W E HopkinsB Barzilai
Jun 1, 1991·The American Journal of Medicine·J M HouraniM S Simmons
Mar 1, 1990·Journal of Hepatology·A G AgustíR Rodriguez-Roisin
Dec 19, 1987·Lancet·C J Dickinson, J F Martin
Jan 1, 1988·Gut·C BabbsN Y Haboubi
Aug 1, 1973·The British Journal of Surgery·R N PughR Williams
Dec 11, 1969·The New England Journal of Medicine·M Altman, E D Robin
May 1, 1984·The American Journal of the Medical Sciences·T FurukawaK Inokuchi
Apr 1, 1995·Annals of Internal Medicine·P A Lange, J K Stoller
Jun 1, 1993·European Journal of Clinical Investigation·C J Dickinson
Mar 1, 1996·Clinics in Chest Medicine·P A Lange, J K Stoller
Jan 31, 1998·Revue médicale de Liège·A LamproyeJ Belaiche
Aug 8, 1998·Journal of Hepatology·M K WhyteA K Burroughs
Aug 26, 1998·Clinical Nuclear Medicine·V IzquierdoC Martinéz de Vírgala
Jan 13, 2001·Journal of Viral Hepatitis·A RegevE R Schiff
Apr 20, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Gary A AbramsMichael B Fallon
Jul 30, 2002·European Journal of Internal Medicine·Gerlinde TeuberStefan Zeuzem
Sep 1, 1956·The American Journal of Medicine·F W HOFFBAUER, R RYDELL
Oct 1, 2003·Gastroenterology·Peter SchenkChristian Müller
Nov 2, 2004·The European Respiratory Journal·R Rodríguez-RoisinUNKNOWN ERS Task Force Pulmonary-Hepatic Vascular Disorders (PHD) Scientific Committee
Apr 14, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Karen L SwansonMichael J Krowka
Nov 30, 2005·Current Treatment Options in Gastroenterology·Miguel R Arguedas, Michael B Fallon

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Citations

Jan 30, 2015·Liver International : Official Journal of the International Association for the Study of the Liver·Sarah RaevensIsabelle Colle
Apr 29, 2014·Liver International : Official Journal of the International Association for the Study of the Liver·Sarah RaevensIsabelle Colle
Jul 21, 2011·Liver International : Official Journal of the International Association for the Study of the Liver·Sophia PourikiDimitrios Pectasides
Sep 4, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Søren MøllerFlemming Bendtsen
Dec 17, 2009·São Paulo Medical Journal = Revista Paulista De Medicina·Liana Gonçalves de Macêdo, Edmundo Pessoa de Almeida Lopes
Nov 2, 2017·Einstein·José Leonardo Faustini PereiraCláudio Augusto Marroni
Jan 30, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Karen L Swanson
May 4, 2007·Nature Clinical Practice. Gastroenterology & Hepatology·A James Hanje, Tushar Patel
Aug 2, 2007·Nature Clinical Practice. Gastroenterology & Hepatology·Takuya Kimura, Augusto Lauro
Apr 25, 2007·Scandinavian Journal of Gastroenterology·Søren MøllerFlemming Bendtsen
Nov 18, 2014·World Journal of Gastroenterology : WJG·Søren MøllerFlemming Bendtsen
Jan 16, 2020·Journal of Pediatric Gastroenterology and Nutrition·Pandey SnehavardhanSeema Alam
Jun 27, 2015·Digestive Diseases and Sciences·Søren Møller, Flemming Bendtsen
Feb 18, 2011·Digestive Diseases and Sciences·Rajan KocharMichael B Fallon
Mar 4, 2015·Digestive Diseases and Sciences·Yong Lv, Daiming Fan
Mar 31, 2018·World Journal of Gastroenterology : WJG·Stergios SoulaidopoulosIoannis Goulis

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Statistical Analysis System (

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