PMID: 43669Nov 1, 1979

Hepatotoxicity of salicylazosulfapyridine: a case report and review of the literature

The American Journal of Gastroenterology
R M GulleyC E Kelly

Abstract

A case report of a patient with biopsy-proven hepatitis which occurred while that patient was receiving Azulfidine which recurred after a rechallenge is presented. Toxic hepatitis, an apparent drug hypersensitivity reaction can result from Azulfidine therapy and must be considered in the differential diagnosis of hepatic abnormalities in patients with inflammatory bowel disease who are taking this drug. The literature concerning toxic reactions to the drug is reviewed.

Related Concepts

Hepatitis
Sulfasalazin medac
Drug-Induced Acute Liver Injury
Drug-Induced Liver Injury
Inflammatory Bowel Diseases
Drug Allergy

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