PMID: 3321096Jan 1, 1986Paper

Hepoxilins, potential endogenous mediators of insulin release

Progress in Lipid Research
C R Pace-AsciakE J Corey

Abstract

Evidence is presented to show that pancreatic islets of Langerhans are capable of producing hepoxilins A3 and B3 from endogenous substrates as well as 14C-labeled 12-HPETE. Both hepoxilins are active in stimulating the release of insulin from these cells in the presence of 10 mM glucose. These experiments suggest that the hepoxilins may participate as potential endogenous mediators of insulin release in islets of Langerhans.

References

Oct 1, 1965·The Journal of Clinical Endocrinology and Metabolism·V HerbertS J Bleicher
Nov 1, 1984·Prostaglandins, Leukotrienes, and Medicine·C R Pace-Asciak, J M Martin
Feb 26, 1982·European Journal of Pharmacology·S YamamotoR Kato

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Citations

Oct 19, 2011·Cancer Metastasis Reviews·Cecil R Pace-Asciak
Nov 17, 1994·Biochimica Et Biophysica Acta·C R Pace-Asciak
Jul 1, 1993·General Pharmacology·C R Pace-Asciak
Feb 27, 2009·Journal of Lipid Research·Matthew W BuczynskiEdward A Dennis
Nov 24, 1999·FEBS Letters·C R Pace-AsciakG Liu
May 9, 2009·British Journal of Pharmacology·Cecil R Pace-Asciak
Mar 8, 2005·Progress in Lipid Research·John W NewmanBruce D Hammock
Sep 23, 2014·Biochimica Et Biophysica Acta·Cecil R Pace-Asciak
Feb 29, 1988·Biochemical and Biophysical Research Communications·C R Pace-Asciak
Sep 30, 1987·Biochemical and Biophysical Research Communications·C R Pace-AsciakJ M Martin

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