PMID: 733681Aug 1, 1978Paper

Herbal medicines and veno-occlusive disease in India

Postgraduate Medical Journal
D V DattaP N Chhuttani

Abstract

Six cases are described of veno-occlusive disease (VOD) after medicinal herb ingestion. The herb Heliotropium eichwaldii, taken by three patients, was found to contain the toxic pyrrolizidine alkaloid, heliotrine. Two patients presented with fulminant hepatic failure while the other four patients had a clinical picture suggestive of decompensated cirrhosis. The medical use of this herb may possibly be responsible for a significant proportion of acute and chronic liver disease in India, making it of public health importance.

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Citations

May 1, 1995·Toxicon : Official Journal of the International Society on Toxinology·C C Yan, R J Huxtable
Jul 1, 1985·Journal of Ethnopharmacology·S N ArseculeratneR G Panabokke
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Mar 3, 2007·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·F Stickel, D Schuppan
Aug 29, 2007·Clinics in Liver Disease·Leonard B Seeff
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May 19, 2020·Archives of Toxicology·Johanna EbmeyerStefanie Hessel-Pras
Sep 21, 2005·Journal of Hepatology·Felix StickelDetlef Schuppan

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