Herbal medicines for metabolic diseases with blood stasis: A protocol for a systematic review and meta-analysis

Medicine
Mi Mi KoJeeyoun Jung

Abstract

Herbal medicines have the potential to be alternative treatments for metabolic diseases. This systematic review will assess the efficacy of herbal medicines in treating metabolic diseases with blood stasis. We will search MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, 2 Korean medical databases (OASIS, NDSL), a Chinese database (China National Knowledge Infrastructure, CNKI), and a Japanese database (J-STAGE) for relevant literature. We will include all randomized controlled trials (RCTs) or quasi-RCTs evaluating the effectiveness of herbal medicine. Participants of both sexes and of any age with clinically diagnosed metabolic disease with blood stasis will be included. Primary outcomes will include Blood-stasis syndrome score, TC, TG, HDL-C and LDL-C. Secondary outcomes will Blood pressure, FBS. ECG, prevalence rate of heart disease, and response rate. The risk of bias will be assessed using the Cochrane tool for assessing risk of bias. The findings of this study will provide a summary of the current state of evidence regarding the effectiveness of types of herbal medicine in managing metabolic disease with blood stasis. In addition, this review will be expected to provide a base for cli...Continue Reading

References

Oct 31, 2008·Endocrine Reviews·Marc-Andre CornierRobert H Eckel
May 2, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Si-Yuan PanKam-Ming Ko
May 24, 2015·European Journal of Pharmacology·Kathleen A MartinArya Mani
Jul 15, 2015·Journal of Diabetes and Metabolic Disorders·Ozra Tabatabaei-MalazyMohammad Abdollahi
May 3, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Haidan YuanGuangchun Piao
Jul 15, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Soobin JangSeong-Gyu Ko
Sep 10, 2016·BMC Complementary and Alternative Medicine·Sun Haeng ParkHo Kyoung Kim
Oct 18, 2016·Drug Safety - Case Reports·Stephanie ChamBeatrice A Golomb
Nov 22, 2016·Lipid Insights·Jonathan T DaviesHollie I Swanson
Dec 27, 2011·Journal of Comorbidity·Alessandro NobiliPier Mannuccio Mannucci

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