Hereditary cancer risk notification and testing: how interested is the general population?

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
M A AndrykowskiR K Munn

Abstract

Great interest in predictive testing for hereditary cancer syndromes has been reported. Prior research has focused on testing for specific hereditary syndromes and/or among individuals at high risk for positive carrier status. Given anticipated expansion of both the range of hereditary syndromes for which testing will be available, as well as the clinical settings in which testing will occur, assessment of interest in hereditary cancer risk testing and notification in the general public is warranted. As part of an annual statewide telephone survey, adults' (N = 654) interest in hereditary cancer risk testing and notification was assessed. Interest in both risk testing (82%) and risk notification (87%) was high. Logistic regression analyses indicated that disinterest in risk notification was associated with female sex, performance of fewer health protective behaviors, and better perceptions of personal health. Disinterest in risk testing was associated with these same variables as well as older age, less concern over developing cancer, and a more extensive history of cancer in first degree relatives. In the absence of risk-reducing behaviors with demonstrable efficacy, hereditary risk testing programs may have difficulty attract...Continue Reading

Citations

Jun 10, 2003·American Journal of Medical Genetics. Part a·A N FreedmanR Ballard-Barbash
Sep 23, 2003·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Christine E KoilKaren M Huelsman
Oct 7, 2006·Human Genetics·Mary E SegalPamela Sankar
Dec 19, 2006·Genetics in Medicine : Official Journal of the American College of Medical Genetics·June A PetersMark H Greene
Jun 1, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R SalovaaraA de la Chapelle
Dec 9, 2003·Genetic Testing·Cécile BlandyClaire Julian-Reynier
Dec 18, 2004·Journal of Genetic Counseling·Kimberly KellyMarvin Schwalb
Sep 18, 2001·Health Affairs·P J NeumannK S Kosik
Feb 5, 2003·American Journal of Medical Genetics. Part a·Katrina ArmstrongJ Sanford Schwartz
Jun 1, 2005·Community Genetics·Elizabeth Campbell, Lainie Friedman Ross
May 14, 2004·Genetic Testing·Eleanor SingerJohn Van Hoewyk
Jul 23, 2005·Journal of Health Communication·Abigail RoseKatrina Armstrong
Jan 18, 2008·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Angela R BradburyChristopher K Daugherty
May 3, 2014·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Michael J HallMary B Daly
Mar 29, 2014·Journal of Genetic Counseling·Kimberly M KellyMichael Andrykowski
Mar 20, 2002·Cancer Practice·M A DiefenbachL Brower
Apr 11, 2000·American Journal of Medical Genetics·K A JohnsonC A Griffin
Jan 29, 2005·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·I MestersH De Vries
Feb 3, 2005·Genetic Testing·Peter T Rowley
Nov 17, 2007·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Susan PerskyColleen M McBride
Feb 16, 2011·The Pharmacogenomics Journal·S B HagaR Agans
May 14, 2004·Genetic Testing·Starlene LoaderPeter T Rowley
Mar 30, 2013·Genetic Testing and Molecular Biomarkers·Lori-Ann A DaleyCharmaine D Royal
Apr 1, 2003·Journal of Genetic Counseling·Lisa M PaglieraniRichard J Wenstrup

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
A H Caulfeild
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
T F Collins
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
P B Fourie
© 2021 Meta ULC. All rights reserved