Hereditary Colorectal Cancer Syndromes

The Surgical Clinics of North America
Katerina Wells, Paul E Wise

Abstract

Awareness of hereditary colorectal cancer syndromes is important to facilitate their identification because affected patients are at increased risk for early onset, synchronous, and metachronous colorectal malignancies, and certain extracolonic malignancies depending on the syndrome. Identification of an affected individual allows for screening and early interventions for patients and their at-risk kindred. Genetic counseling and testing is important to the care of these patients. As knowledge of the genetic basis of these syndromes grows, unique genotype-phenotype profiles allow clinicians to tailor surveillance and treatment strategies based on individual risk.

Citations

Jun 1, 2018·Case Reports in Pathology·Erin BaumgartnerDeniz Peker
Sep 12, 2020·International Journal of Molecular Sciences·K V Surangi DharmawansaH P Vasantha Rupasinghe
Dec 23, 2020·Problemy e̊ndokrinologii·Elena E BaranovaIgor E Hat'kov
Dec 29, 2021·Annals of Coloproctology·Jin Cheon Kim, Walter F Bodmer

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