PMID: 11310711Apr 20, 2001Paper

Heredity versus abnormalities in pregnancy and delivery as risk factors for different types of comitant strabismus

Journal of Pediatric Ophthalmology and Strabismus
T MatsuoH Ohtsuki

Abstract

To elucidate risk factors for different types of comitant strabismus, the incidence of heredity and abnormalities in pregnancy and delivery was compared among different types of strabismus. Between May 1998 and January 1999, a prospective clinical study of 500 consecutive patients with comitant strabismus at a referral-based university hospital was performed using data collected from questionnaires and interviews. Inclusion criteria were infantile esotropia (168 patients), accommodative and partially accommodative esotropia (97 patients), microesotropia (15 patients), acquired esotropia (12 patients), intermittent or constant exotropia (205 patients), and congenital exotropia (3 patients). Exclusion criteria were strabismus associated with systemic and central nervous system abnormalities and organic eye diseases. Family history was significantly more prevalent in intermittent or constant exotropia and accommodative or partially accommodative esotropia than in infantile esotropia (P<.0001 and P=.0267, respectively, Fisher's exact test). In contrast, abnormalities in pregnancy and delivery were noted at a significantly higher rate in infantile esotropia than in accommodative or partially accommodative and in intermittent or cons...Continue Reading

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