Heritability of hallucinations in adolescent twins

Psychiatry Research
Yoon-Mi HurPak C Sham

Abstract

Hallucinations are common in normal individuals and patients with schizophrenia and other psychotic disorders. Traditionally psycho-social approaches have emphasized the importance of environmental factors that contribute to variation of hallucinations. Using the Launay-Slade Hallucination Scale-Revised (LSHS-R), we investigated genetic and environmental influences on hallucinations in 598 pairs of healthy South Korean adolescent twins. Parameter estimates in the best-fitting model indicated that additive genetic and individual specific environmental factors for the LSHS-R were 33% (95% CI: 23-42%) and 67% (95% CI: 60-77%), respectively. There was no evidence for sex-specific genes for hallucinations. The magnitudes of genetic and environmental influences on hallucinations were similar in males and females. These results have implications in future molecular genetic studies that search for genes for hallucinations.

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Citations

Feb 16, 2016·Psychophysiology·Christopher J Patrick, Greg Hajcak
Apr 9, 2016·The British Journal of Psychiatry : the Journal of Mental Science·Sania ShakoorAngelica Ronald
Jun 18, 2014·Schizophrenia Bulletin·Renaud JardriCharles Fernyhough
Apr 1, 2018·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Oliver PainAngelica Ronald
Dec 1, 2012·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Yoon-Mi HurTae-Bok Song
Dec 27, 2019·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Yoon-Mi HurJong Woo Kim
Mar 11, 2020·Translational Psychiatry·Wikus BarkhuizenAngelica Ronald
Apr 9, 2019·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Laura HaversAngelica Ronald

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