PMID: 8580553Sep 1, 1995Paper

Herpes simplex virus type 2 infections presenting as brainstem encephalitis and recurrent myelitis

Internal Medicine
H NakajimaN Ohsawa

Abstract

We describe here 3 patients with central nervous system infection caused by herpes simplex virus type 2 (HSV-2); one patient with brainstem encephalitis and two with recurrent transverse thoracic myelitis. All three patients showed increased IgG antibodies to HSV in the cerebrospinal fluid (CSF). HSV-2 DNA was demonstrated in the CSF by polymerase chain reaction (PCR) amplification. Upon treatment with acyclovir, one patient with myelitis partially recovered and the others completely recovered. It is important to recognize the wide spectrum of clinical manifestations of HSV-2 infection in the central nervous system (CNS).

Citations

May 25, 2010·Journal of Neurology·Daniel LivorsiCarlos Franco-Paredes
May 18, 2000·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·A SauerbreiP Wutzler
Jul 2, 2002·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Sophie MinjolleRonald Colimon
Sep 15, 2001·Brain Pathology·B K Kleinschmidt-DeMastersK L Tyler
Feb 10, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Shiroh MiuraTakayuki Taniwaki
Oct 29, 2011·Neuroimaging Clinics of North America·Christine GohPatricia M Desmond
Aug 26, 2014·The American Journal of Medicine·Jayaram Subhashchandra BallaekereAshok Parameshwarappa
Sep 24, 1999·The Pediatric Infectious Disease Journal·J T Atkins
Dec 24, 2019·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Elena AbatiStefania Corti
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May 26, 2017·Frontiers in Neurology·Raffaele NardoneJohann Sellner
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