PMID: 11898565Mar 20, 2002Paper

Herpes zoster infection and postherpetic neuralgia

Current Neurology and Neuroscience Reports
R B Tenser

Abstract

Varicella-zoster virus (VZV), the cause of chicken pox, establishes latent infection in sensory ganglia. Reactivation results in zoster (shingles), sometimes complicated by encephalitis (myelitis). Postherpetic neuralgia (PHN) is the major morbidity of zoster. PHN typically increases in frequency with age. The VZV vaccine, which was developed for children, may be effective in enhancing VZV immune reactivity and decreasing zoster in adults. Early antiviral treatment may be effective in decreasing PHN onset. Several other medications may be useful in treating established PHN. A recent report discussed intrathecal steroid use.

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Aug 5, 2003·Antiviral Research·Robert J Visalli, Marja van Zeijl
Dec 13, 2006·Pain Practice : the Official Journal of World Institute of Pain·C Peter N Watson, Anne Louise Oaklander
May 9, 2014·Journal of Virology·Melissa A VisalliRobert J Visalli
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May 7, 2020·Pain Practice : the Official Journal of World Institute of Pain·Gang XuKai Hua Ding
Jul 15, 2015·The Journal of Craniofacial Surgery·Guo-wei LiWen-chuan Zhang

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