Heterochrony and the phylotypic period

Developmental Biology
M K Richardson

Abstract

There has been a resurgence of interest in comparative embryology. It is now important to be able to compare gene expression in different species at similar developmental stages. One phenomenon which may make it difficult to compare embryos in this way is heterochrony--a change in developmental timing during evolution. It is not clear whether heterochrony can affect the intermediate stages of embryonic development, when many important genes involved in pattern formation are expressed. A prevalent view is that these so-called phylotypic stages are resistant to evolutionary change because they are when the body plan is laid down. Haeckel's famous drawings, which show different vertebrates developing from virtually identical somite-stage embryos, are still used to support this idea. I have reexamined the morphological data relating to developmental timing in somite-stage embryos. The data reveal striking patterns of heterochrony during vertebrate evolution. These shifts in developmental timing have strongly affected the phylotypic stage, which is therefore poorly conserved and is more appropriately described as the phylotypic period. This is contrary to the impression created by Haeckel's drawings, which I show to be inaccurate an...Continue Reading

Citations

Feb 13, 1999·Archives of Insect Biochemistry and Physiology·R FarkasD Jones
Sep 3, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M K Richardson
Feb 11, 2012·Theory in Biosciences = Theorie in Den Biowissenschaften·Jana Svorcová
Apr 1, 1998·Trends in Ecology & Evolution·M K RichardsonJ Hanken
May 3, 2003·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Susan J Crockford
Dec 12, 2002·Biological Reviews of the Cambridge Philosophical Society·Michael K Richardson, Gerhard Keuck
Mar 24, 2011·Nature Communications·Naoki Irie, Shigeru Kuratani
Jul 14, 2011·Physical Biology·Michelangelo von Dassow, Lance A Davidson
Mar 18, 2003·Proceedings. Biological Sciences·Olaf R P Bininda-EmondsMichael K Richardson
Oct 2, 2002·Evolution; International Journal of Organic Evolution·Philip A Hastings
Oct 29, 2005·Brain, Behavior and Evolution·Michael B Pritz
Oct 3, 2007·BMC Evolutionary Biology·Olaf R P Bininda-EmondsMichael K Richardson
Jun 13, 2009·PloS One·Ingmar Werneburg
Aug 23, 2001·Proceedings of the National Academy of Sciences of the United States of America·R KollmarA J Hudspeth
Jan 5, 2000·Proceedings of the National Academy of Sciences of the United States of America·J KimG S Min
Aug 10, 2002·Evolution & Development·Mark W Hamrick
Aug 10, 2002·Evolution & Development·Jonathan E JefferyMichael K Richardson
Oct 13, 2004·The American Naturalist·Steven Poe, Marvalee H Wake
Feb 5, 2011·Journal of Chemical Neuroanatomy·M J DoldánE de Miguel Villegas
Dec 19, 2015·BMC Evolutionary Biology·Ariel D Chipman
Aug 5, 2015·Mechanisms of Development·Joost M Woltering, Denis Duboule
May 7, 2005·Evolution & Development·Philipp MitteroeckerFred L Bookstein
Nov 3, 2009·Evolution & Development·Ilse M L de JongMichael K Richardson
Mar 7, 2009·The Journal of Comparative Neurology·Christine J Charvet, Georg F Striedter
Feb 12, 2009·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Valerie Christine Virta, Mark Scott Cooper
Mar 8, 2003·Evolution & Development·Janet L Vaglia, Kathleen K Smith
Jan 9, 2009·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Michael K RichardsonMarcelo R Sánchez-Villagra
Mar 21, 2007·Evolution & Development·Jennifer J SmirthwaiteJohn I Spicer
Oct 1, 2013·Evolution & Development·Robin M AndrewsVirginia W Greene
Feb 26, 2016·Molecular Biology and Evolution·Hajk-Georg DrostMarcel Quint
Sep 11, 2010·American Journal of Medical Genetics. Part a·Marco OliverioBruno Marino
Feb 18, 2011·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Kai Schmidt, J Matthias Starck
May 4, 2010·Evolution & Development·Aurélie ComteMarc Robinson-Rechavi
Jun 16, 2010·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Richard P Elinson, Lorren Kezmoh
Mar 26, 2016·Annals of Botany·Andrew G CridgeLynette R Brownfield
Jun 9, 2004·Journal of Human Evolution·Philipp MitteroeckerFred L Bookstein
Dec 20, 2002·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Klaus Sander
Dec 15, 2005·Zoology : Analysis of Complex Systems, ZACS·M K RichardsonO R Bininda-Emonds
Dec 15, 2005·Zoology : Analysis of Complex Systems, ZACS·Jonas Blom, Clas Lilja
May 15, 2015·Biological Reviews of the Cambridge Philosophical Society·Andrew I Furness

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