Heterogeneity of bla(IND) metallo-beta-lactamase-producing Chryseobacterium indologenes isolates detected in Hefei, China

International Journal of Antimicrobial Agents
Xiang-Hong LinZhong-Xin Wang

Abstract

This study investigated the phenotypic and genetic properties of 28 clinical isolates of metallo-beta-lactamase (MBL)-producing Chryseobacterium indologenes recovered from a university hospital. Twenty isolates were confirmed to carry a bla(IND) gene. Among them, 9 isolates were confirmed to carry the IND-1 gene, 10 contained the IND-2 gene and 1 had bla(IND-3) alleles. One strain (No. 7) confirmed to be carrying the bla(IND-1) gene was susceptible to imipenem and was negative in phenotypic methods. The data revealed that the antimicrobial resistance patterns of C. indologenes harbouring MBL genes are remarkably distinct. Two specific types of MBL genes, bla(IND-1) and bla(IND-2), were identified to be the major genotype for C. indologenes isolated from Hefei, China.

References

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Citations

Nov 8, 2012·World Journal of Microbiology & Biotechnology·Ana MaravićJasna Puizina
Nov 16, 2011·Antimicrobial Agents and Chemotherapy·Takehisa MatsumotoTakayuki Honda
Feb 1, 2012·Antimicrobial Agents and Chemotherapy·Lisandro J González, Alejandro J Vila
Nov 29, 2012·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·V KumarS Kumari
May 17, 2011·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Anuradha S DeSujata M Baveja

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