PMID: 8989928Dec 1, 1996Paper

Heterogeneity of Borrelia burgdorferi in the skin

The American Journal of Dermatopathology
E AbererW Jurecka

Abstract

The reliability of various in vitro techniques to identify Borrelia burgdorferi infection is still unsatisfactory. Using a high-power resolution videomicroscope and staining with the borrelia genus-specific monoclonal flagellar antibody H9724, we identified borrelial structures in skin biopsies of erythema chronicum migrans (from which borrelia later was cultured), of acrodermatitis chronica atrophicans, and of morphea. In addition to typical borreliae, we noted stained structures of varying shapes identical to borreliae found in a "borrelia-injected skin" model; identical to agar-embedded borreliae; and identical to cultured borreliae following exposure to hyperimmune sera and/or antibiotics. We conclude that the H9724-reactive structures represent various forms of B. burgdorferi rather than staining artifacts. These "atypical" forms of B. burgdorferi may represent in vivo morphologic variants of this bacterium.

References

Aug 1, 1992·The Journal of Infectious Diseases·K GeorgilisM S Klempner
Aug 1, 1986·Journal of the American Academy of Dermatology·H K ParkA G Barbour
May 1, 1987·Journal of Medical Microbiology·J De KoningJ A Hoogkamp-Korstanje
May 1, 1989·Infection and Immunity·L E Comstock, D D Thomas
Jan 1, 1989·Journal of Basic Microbiology·D HulínskáJ Herzogová
Apr 1, 1988·The Pediatric Infectious Disease Journal·K WeberP H Duray
Jul 1, 1987·Human Pathology·A B MacDonald, J M Miranda
Oct 1, 1987·The American Journal of Dermatopathology·E Aberer, G Stanek
May 1, 1988·Annals of Internal Medicine·M H GoellnerP H Duray
May 1, 1986·Infection and Immunity·A G BarbourS L Tessier
Dec 1, 1986·Zentralblatt Für Bakteriologie, Mikrobiologie, Und Hygiene. Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology·V Preac-MursicG Schierz
Aug 1, 1987·European Journal of Clinical Microbiology·V P MursicE Süss
Nov 1, 1987·Journal of Clinical Microbiology·T J KurttiG G Ahlstrand
Jul 1, 1985·Annals of Internal Medicine·P A SchlesingerM T Stillman
Apr 1, 1983·The American Journal of Dermatopathology·B W BergerA B Ackerman
Jun 1, 1983·Journal of Bacteriology·S F HayesA G Barbour
May 1, 1982·Antimicrobial Agents and Chemotherapy·A G BarbourH G Stoenner
May 1, 1995·Antimicrobial Agents and Chemotherapy·A KerstenE Aberer
Jan 1, 1993·Dermatology : International Journal for Clinical and Investigative Dermatology·P Van MierloP Dockx
Apr 1, 1951·The Journal of Investigative Dermatology·E D DeLAMATERD M PILLSBURY

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Citations

Apr 25, 2003·Medical Hypotheses·W T Harvey, P Salvato
May 3, 2000·The British Journal of Dermatology·B WeideC Garbe
Jul 16, 2010·International Journal of Dentistry·L Sonnesen
Sep 27, 2008·Journal of Neuroinflammation·Judith MiklossyPatrick L McGeer
Dec 18, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Paul M LantosGary P Wormser
Nov 13, 2007·Médecine et maladies infectieuses·P Moguelet
Jan 11, 2007·American Journal of Clinical Pathology·Klaus EisendleBernhard Zelger
Nov 21, 2007·Journal of the American Academy of Dermatology·Bernhard ZelgerBettina Zelger
Mar 30, 2007·Médecine et maladies infectieuses·D Lipsker
Feb 14, 2004·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·R Murgia, M Cinco
Jul 12, 2008·Journal of Cutaneous Pathology·Mirjana ZiemerBernhard Zelger
Oct 19, 2007·The British Journal of Dermatology·K EisendleB Zelger
Oct 23, 2010·Journal of Basic Microbiology·Samiya Al-RobaiyReinhard K Straubinger
Mar 15, 2006·International Journal of Medical Microbiology : IJMM·Klaus-Peter HunfeldFranc Strle
Jan 8, 2015·Microbiology·Leena MeriläinenLeona Gilbert
May 23, 2015·Infectious Disease Clinics of North America·Adriana R Marques
May 4, 2016·Microbes and Infection·Leena MeriläinenLeona Gilbert
Apr 25, 2007·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Elisabeth Aberer
Oct 16, 2015·Jundishapur Journal of Microbiology·Mohhamad Javad YazdanpanahKiarash Ghazvini
Feb 24, 2015·The American Journal of Dermatopathology·Ana María Molina-RuizLuis Requena
May 18, 2019·Parasites & Vectors·Natalie RudenkoMarie Vancova
Apr 18, 2018·Healthcare·Marianne J MiddelveenRaphael B Stricker
Jan 1, 2020·Antibiotics·Samuel ShorElizabeth L Maloney
Jan 1, 2020·Pathogens·Vladimir V BammMelanie K B Wills
May 2, 2002·The Medical Clinics of North America·Jonas Bunikis, Alan G Barbour

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