PMID: 2730892Jun 8, 1989Paper

Heterogeneity of cellular expression of arachidonate 15-lipoxygenase: implications for biological activity

Biochimica Et Biophysica Acta
M J HoltzmanJ R Hansbrough


Comparison of relative arachidonate 15-lipoxygenase activities in different types of human cell reveals striking differences in levels of product generation. Among available human cell types, the tracheal epithelial cell and the eosinophil have markedly higher levels of activity than other cell types with reported activity. Theories of functional significance for this enzymatic pathway will need to account for the selective expression of high levels of activity in a highly limited number of cell types.


Feb 13, 1986·Biochemical and Biophysical Research Communications·A HanssonB Samuelsson
Aug 1, 1986·Prostaglandins, Leukotrienes, and Medicine·J CookM Kazatchkine
Jan 1, 1986·The Journal of Clinical Investigation·A P Pentland, P Needleman
Dec 22, 1986·Biochimica Et Biophysica Acta·S M Rapoport, T Schewe
Jan 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·R A DixonC A Rouzer
Jul 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J A HunterM J Holtzman
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Jul 1, 1983·The Journal of Clinical Investigation·Z MaromM Kaliner
Feb 1, 1982·Prostaglandins, Leukotrienes, and Medicine·J L CopasP J Gardiner

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Nov 15, 1994·Annals of the New York Academy of Sciences·M J HoltzmanJ D Wilson
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