PMID: 2730892Jun 8, 1989Paper

Heterogeneity of cellular expression of arachidonate 15-lipoxygenase: implications for biological activity

Biochimica Et Biophysica Acta
M J HoltzmanJ R Hansbrough

Abstract

Comparison of relative arachidonate 15-lipoxygenase activities in different types of human cell reveals striking differences in levels of product generation. Among available human cell types, the tracheal epithelial cell and the eosinophil have markedly higher levels of activity than other cell types with reported activity. Theories of functional significance for this enzymatic pathway will need to account for the selective expression of high levels of activity in a highly limited number of cell types.

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Citations

Nov 15, 1994·Annals of the New York Academy of Sciences·M J HoltzmanJ D Wilson
Nov 1, 1994·American Journal of Respiratory and Critical Care Medicine·S I RennardJ R Spurzem
Sep 1, 1989·American Journal of Respiratory Cell and Molecular Biology·J R HansbroughM J Holtzman
Mar 1, 1993·American Journal of Respiratory Cell and Molecular Biology·S E Alpert, R W Walenga
Feb 1, 1994·The Journal of Clinical Investigation·T WuJ H Shelhamer
Nov 9, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H KoskelaC Katelaris
Apr 6, 1995·Biochimica Et Biophysica Acta·L LomnitskiS Grossman
Aug 1, 1991·The Journal of Investigative Dermatology·H H Henneicke-von ZepelinE Christophers
Jan 1, 1994·The Journal of Investigative Dermatology·N GodessartJ M de Moragas

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