Heterogeneity of delusional syndromes: diagnostic criteria and course prognosis

Psychopathology
H SchandaP Berner

Abstract

In addition to genetic findings and treatment response, the course prognosis is also meant to be a possible validating criterion for diagnosis and diagnostic systems. In our study we used the polydiagnostic approach (i.e. the simultaneous application of various criteria for diagnosing a given disorder to one and the same population) to test the ability of several diagnostic systems to create homogeneous groups regarding the course (episodic/chronic). We applied Schneider's FRS, ICD-9, DSM-III, Spitzer's RDC and the Vienna Research Criteria to 90 patients with the diagnosis of delusional syndrome (aside from any nosological classification), who underwent 6-9 years of follow-up. At the index examination, schizophrenia was most frequently diagnosed with Schneider's FRS, which apparently encompasses a very heterogeneous group of patients regarding psychopathology and course. Diagnostic systems which allowed the diagnosis of affective disorders despite the presence of mood-incongruent delusional symptomatology (DSM-III, RDC, Vienna Criteria) or offered the diagnosis of schizoaffective disorder (DSM-III, RDC) succeeded in separating subgroups with an episodic course on a statistically significant level. In ICD-9 this significance app...Continue Reading

Citations

Dec 13, 2006·Schizophrenia Bulletin·Lennart B Jansson, Josef Parnas
Jan 26, 2005·International Journal of Psychiatry in Medicine·Lydia Gayubo MoreoAlicia García Recio
Apr 17, 2015·The Cochrane Database of Systematic Reviews·Karla Soares-WeiserClive E Adams

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