PMID: 3322168Mar 1, 1986Paper

Heterogeneity of genes conferring high-level resistance to erythromycin by inactivation in enterobacteria

Annales De L'Institut Pasteur. Microbiology
M ArthurP Courvalin

Abstract

We have constructed a probe specific for the gene ereA of plasmid pIP1100, which confers high-level resistance to erythromycin in Escherichia by production of an erythromycin esterase. The distribution of the gene ereA in enterobacteria highly resistant to erythromycin isolated from human faeces was studied by colony hybridization. The gene ereA was detected in strains of E. coli belonging to various biotypes, in Klebsiella pneumoniae, in Enterobacter agglomerans and in one strain of a "coliform". Moreover, our results indicated the existence of at least two classes of genes specifying resistance to erythromycin by inactivation of the antibiotic in enterobacteria.

References

Apr 1, 1977·Antimicrobial Agents and Chemotherapy·P Courvalin, J Davies
Mar 1, 1976·Bacteriological Reviews·R P NovickS Falkow
Jul 1, 1985·The Journal of Antimicrobial Chemotherapy·P CourvalinM Arthur
May 14, 1969·Journal of Molecular Biology·H W Boyer, D Roulland-Dussoix
Dec 25, 1982·Journal of Molecular Biology·F SangerG B Petersen
Dec 1, 1984·The Journal of Antibiotics·P BarthélémyP Courvalin

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Citations

Nov 1, 1986·Antimicrobial Agents and Chemotherapy·M Arthur, P Courvalin
Oct 28, 2016·Critical Reviews in Microbiology·Cláudia GomesJoaquim Ruiz
Jun 12, 2008·Biographical Memoirs of Fellows of the Royal Society·Robin Holliday, Richard B Flavell
Aug 1, 1992·Journal of Clinical Microbiology·P Saulnier, A Andremont

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