Heterogeneity of perinatal outcomes in the preterm delivery syndrome

Obstetrics and Gynecology
José VillarWorld Health Organization Antenatal Care Trial Research Group

Abstract

Our aim was to document the differential neonatal morbidity and intrapartum and neonatal mortality of subgroups of preterm delivery. This analysis included 38,319 singleton pregnancies, of which 3,304 (8.6%) were preterm deliveries (less than 37 completed weeks) enrolled in the World Health Organization randomized trial of a new antenatal care model. We classified them as preterm deliveries after spontaneous initiation of labor, either with or without maternal obstetric and medical complications; preterm deliveries after prelabor spontaneous rupture of amniotic membranes (PROM), either with or without obstetric and medical complications; and medically indicated preterm deliveries with maternal obstetric and medical complications. Severe neonatal morbidity and neonatal mortality were the primary outcomes. Fifty-six percent of all preterm deliveries were spontaneous, without maternal complications. Small for gestational age was increased only among the medically indicated preterm delivery group (22.3%). Very early preterm delivery (less than 32 weeks of gestation) was highest among PROM with complications (37%). For intrapartum fetal death and neonatal death, after adjusting by gestational age and other confounding variables, we ...Continue Reading

References

Feb 1, 1991·American Journal of Obstetrics and Gynecology·D A SavitzJ M Thorp
Sep 1, 1990·American Journal of Obstetrics and Gynecology·J OwenR L Copper
May 1, 1987·American Journal of Obstetrics and Gynecology·P J MeisM L Moore
Apr 1, 1985·American Journal of Obstetrics and Gynecology·D M MainS Strong
Jul 1, 1995·Paediatric and Perinatal Epidemiology·C A BlackmoreW A Bowes
Feb 1, 1995·Obstetrics and Gynecology·M L HedigerR L Fischer
May 1, 1997·The Australian & New Zealand Journal of Obstetrics & Gynaecology·P H GrayH A Mohay
Jan 1, 1997·American Journal of Perinatology·C V AnanthW A Bowes
May 16, 1998·Epidemiology·G S BerkowitzD A Savitz
Nov 7, 1998·Paediatric and Perinatal Epidemiology·J VillarH Berendes
Nov 7, 1998·Paediatric and Perinatal Epidemiology·A DonnerP Lumbiganon
Nov 13, 1998·The New England Journal of Medicine·K S JosephR Platt
Dec 2, 2000·Paediatric and Perinatal Epidemiology·K E PickettS Selvin
Apr 17, 2001·Statistics in Medicine·R P McMahon, F E Harrell
May 30, 2001·Lancet·J VillarUNKNOWN WHO Antenatal Care Trial Research Group
Aug 3, 2001·American Journal of Obstetrics and Gynecology·J A ZeitlinE Papiernik
Aug 25, 2001·The New England Journal of Medicine·M A KlebanoffUNKNOWN National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units
Feb 21, 2002·American Journal of Obstetrics and Gynecology·Shaun McGrathRoger Smith
Sep 13, 2002·American Journal of Epidemiology·Michael S KramerUNKNOWN Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System

❮ Previous
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Citations

Aug 30, 2008·American Journal of Epidemiology·T F McElrathUNKNOWN ELGAN Study Investigators
Apr 22, 2010·Epidemiology·Olga Basso, Allen Wilcox
Mar 27, 2010·BMC Pregnancy and Childbirth·Michael G GravettUNKNOWN GAPPS Review Group
Jul 9, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Panos AntsaklisAris Antsaklis
Aug 4, 2007·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Cande V AnanthAnthony M Vintzileos
May 13, 2006·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Lisa HartlingThierry Lacaze-Masmonteil
Dec 28, 2006·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Cande V Ananth, Anthony M Vintzileos
Aug 26, 2011·Inhalation Toxicology·Regina RückerlAnnette Peters
Nov 26, 2010·Seminars in Perinatology·Lavone E SimmonsMichael G Gravett
May 22, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Wei YuanAndrés López Bernal
Nov 7, 2008·American Journal of Human Biology : the Official Journal of the Human Biology Council·Michelle LamplRoberto Romero
Aug 19, 2007·Paediatric and Perinatal Epidemiology·Nils-Halvdan MorkenBo Jacobsson
May 4, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·G HammondF Stanley
May 18, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·J VillarUNKNOWN International Fetal and Newborn Growth Consortium for the 21st Century
May 18, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·D G AltmanUNKNOWN International Fetal and Newborn Growth Consortium for the 21st Century
Jun 4, 2014·The Journal of Obstetrics and Gynaecology Research·Liang-Kai WangChie-Pein Chen
May 30, 2006·Seminars in Perinatology·Carrie K Shapiro-MendozaStephen Evans
Feb 19, 2008·Clinics in Perinatology·Cande V Ananth, Anthony M Vintzileos
Dec 20, 2011·American Journal of Obstetrics and Gynecology·Jose VillarRobert L Goldenberg
Feb 20, 2007·American Journal of Obstetrics and Gynecology·Craig E PennellCaroline Relton
Apr 4, 2006·American Journal of Obstetrics and Gynecology·José VillarUNKNOWN World Health Organization Antenatal Care Trial Research Group
Aug 11, 2007·American Journal of Obstetrics and Gynecology·Jun ZhangGuillermo Carroli
Sep 5, 2006·American Journal of Obstetrics and Gynecology·Cande V AnanthAnthony M Vintzileos
Sep 10, 2005·American Journal of Obstetrics and Gynecology·Nancy S GreenUNKNOWN March Of Dimes Scientific Advisory Committee On Prematurity
Aug 11, 2012·The Journal of Pediatrics·Beena D Kamath-RayneAimin Chen
Oct 4, 2006·American Journal of Obstetrics and Gynecology·Cande V Ananth, Anthony M Vintzileos
Nov 24, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·M F B de AlmeidaD Campos Junior
Feb 13, 2008·Journal of Psychosomatic Obstetrics and Gynaecology·J JeneweinS Büchi
Jul 2, 2008·Obstetrics and Gynecology·Jodie M DoddCaroline A Crowther
May 2, 2006·Obstetrics and Gynecology·Fernando C Barros, Maria del Pilar Vélez
Aug 25, 2009·Obstetrics and Gynecology·Aimin ChenMichael J Barsoom
Dec 19, 2017·Pharmacoepidemiology and Drug Safety·Jeanne M PimentaChristina Mack
Jun 15, 2018·Journal of Global Health·Karen T ChangJoanne Katz
Sep 3, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·Y W ChengA B Caughey
Jun 9, 2021·Pediatric Research·Sagori Mukhopadhyay, Mark A Underwood
Feb 5, 2008·Pediatrics·Carrie K Shapiro-MendozaEugene Declercq

❮ Previous
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