Heterogeneity of reporting standards in randomised clinical trials of endovenous interventions for varicose veins

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
B ThakurA H Davies

Abstract

The efficacy of endovenous treatments for venous reflux has been demonstrated in numerous randomised clinical trials, although significant heterogeneity may exist between studies. The aim of this study was to assess the heterogeneity in reporting between randomised clinical trials investigating endovenous treatments for patients with varicose veins. A literature search of the Pubmed, Cochrane and Google Scholar databases was performed using appropriate search terms. Randomised clinical trials published between January 1968 and June 2009 evaluating endovenous interventions for varicose veins were included and relevant abstracts and full text articles were reviewed. Published study reports were evaluated against recommended reporting standards published by the American Venous Forum in 2007. Twenty-eight randomised trials fulfilled the inclusion criteria. Median patient age (reported in 20/28 studies) ranged from 33 to 54 years. The CEAP classification was presented in 17/28 studies and the proportion of patients with C2 disease ranged from 6.3% to 83.5%. A total of 31 different outcome measures were utilised. This included 13 different questionnaires, varicose vein recurrence at 38 time points and 30 categories of complications. ...Continue Reading

References

Mar 1, 1979·The British Journal of Surgery·B H Jakobsen
Feb 1, 1994·The British Journal of Surgery·M J Callam
May 29, 1993·BMJ : British Medical Journal·A M GarrattI T Russell
Feb 7, 1993·Quality in Health Care : QHC·A M GarrattZ H Krukowski
Mar 5, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kees-Peter de RoosH A Martino Neumann
Dec 1, 2004·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·F LurieS Schuller-Petrovic
Dec 29, 2004·Journal of Vascular Surgery·Bo EklöfUNKNOWN American Venous Forum International Ad Hoc Committee for Revision of the CEAP Classification
Sep 3, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·R J HinchliffeB D Braithwaite
Oct 20, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·D G BountouroglouG Geroulakos
Dec 13, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Charles Angotti Furtado de Medeiros, George Carchedi Luccas
Mar 4, 2008·American Journal of Infection Control·Trevor M YeungPatrick Lintott
Aug 23, 2008·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·R AbelaY Panayiotopoulos
Dec 30, 2008·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·B C V M DisselhoffF L Moll

❮ Previous
Next ❯

Citations

Mar 30, 2012·Phlebology·S OnidaA H Davies
Dec 22, 2017·Phlebology·Alexander P CouplandAlun H Davies
Jul 19, 2018·São Paulo Medical Journal = Revista Paulista De Medicina·Ricardo de Ávila OliveiraJosé Carlos da Costa Baptista-Silva
Jul 26, 2011·Acta chirurgica Belgica·T R A LaneA H Davies

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.