Heterogeneous treatment effects of a text messaging smoking cessation intervention among university students

PloS One
Marcus Bendtsen

Abstract

Despite tobacco being an important preventable factor with respect to ill health and death, it is a legal substance that harms and kills many of those who use it. Text messaging smoking cessation interventions have been evaluated in a variety of contexts, and are generally considered to have a positive effect on smoking cessation success. In order for text messaging interventions to continue to be useful as prevalence of smoking decreases, it may be necessary to tailor the interventions to specific individuals. However, little is known with regard to who benefits the most and least from existing interventions. In order to identify heterogenous treatment effects, we analyzed data from a randomized controlled trial of a text messaging smoking cessation intervention targeting university students in Sweden. We used a Bayesian hierarchical model where the outcome was modelled using logistic regression, and so-called horseshoe priors were used for coefficients. Predictive performance of the model, and heterogeneous treatment effects, were calculated using cross-validation over the trial data. Findings from the study of heterogenous treatment effects identified less effect of the intervention among university students with stronger de...Continue Reading

References

Jan 31, 2006·American Heart Journal·Adrián V HernándezEwout W Steyerberg
Nov 23, 2007·The New England Journal of Medicine·Rui WangJeffrey M Drazen
May 18, 2011·Annals of Internal Medicine·Tyler J VanderWeele, Mirjam J Knol
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Clinical Trials Mentioned

ISRCTN75766527

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NEXit
R package rstanarm
STAN
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rstanarm

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