Heterosexually acquired human immunodeficiency virus infection and the United States blood supply: considerations for screening of potential blood donors. HIV Blood Donor Study Group

Transfusion
L R PetersenA E Williams

Abstract

The impact of heterosexual transmission of the human immunodeficiency virus (HIV) on the United States blood supply was assessed, and deferral criteria that may exclude potential donors who are at high risk for heterosexually acquired HIV infection were evaluated. Interviews were conducted with 508 HIV-seropositive blood donors from May 1, 1988, to August 31, 1989 (Phase 1), and with 472 donors from January 1, 1990, to May 31, 1991 (Phase 2), at 20 blood centers. From Phase 1 to Phase 2, the overall HIV prevalence decreased from 0.021 to 0.018 percent (p < 0.001). HIV risk factors among HIV-1-seropositive donors were similar during both study phases. Eleven percent of the men and 56 percent of the women reported as their only risk that they had a heterosexual partner who was at increased risk for HIV or was known to have HIV. These percentages were similar during both study periods. During Phase 2, 13 percent of the men and 17 percent of the women with heterosexual transmission risk had a positive serologic test for syphilis, hepatitis B core antibody, or hepatitis C antibody. Among HIV-1-seropositive donors reporting heterosexual risk, the median numbers of previous-year and lifetime sex partners for men were 2 and 30, respect...Continue Reading

Citations

Aug 26, 1998·American Journal of Preventive Medicine·B GerbertM Allerton
Apr 27, 2000·Transfusion Medicine Reviews·A BlancherW W Socha
Apr 5, 2019·Transfusion·Josephine MitchelUNKNOWN Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) South Africa Program
Feb 1, 2003·Transfusion·Ana M SanchezUNKNOWN Retrovirus Epidemiology Donor Study

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