Heterotopic pancreas adenocarcinoma in the stomach: A case report and literature review

World Journal of Clinical Cases
Yao XiongXin-Ying Wang

Abstract

Heterotopic pancreas is a common lesion found in the gastrointestinal tract and is usually considered a benign disease. Reports of malignant change of heterotopic pancreas are scarce. A 44-year-old Chinese female underwent a gastroscopy to assess abdominal distension that had persisted for 2 months. A protruding lesion in the gastric antrum was revealed but no malignant tissue was found in the biopsy specimen. The patient's symptom persisted and progressed to repeated vomiting. Endoscopy after 4 months revealed obstruction of the gastric outlet caused by the protruding lesion. A distal gastrectomy was performed. Histopathological examination of the surgical specimen showed the malignant transformation of aberrant pancreas in the stomach. Chemotherapy consisting of folinic acid, fluorouracil, and oxaliplatin was administered for three cycles, and was changed to gemcitabine monotherapy because of adverse effects and increased serum tumor marker levels. The patient remained asymptomatic during a 12-month follow-up. Pancreatic heterotopy should be considered as source of a potentially malignant lesion, and early treatment or close monitoring for aberrant pancreas is recommended.

References

Mar 1, 1979·Acta Pathologica Japonica·A TanimuraE Sano
Jan 1, 1989·Gastrointestinal Endoscopy·K YasudaK Kawai
Jul 1, 1963·Annals of Surgery·W B GOLDFARBW MONAFO
Feb 18, 2004·Journal of Korean Medical Science·Dong Eun SongJung Sun Kim
Mar 3, 2004·Journal of Clinical Pathology·R Chetty, I Weinreb
Jul 12, 2005·Journal of Gastroenterology·Michiko MatsukiShigeki Kuriyama
Aug 27, 2005·AJR. American Journal of Roentgenology·Khaled M ElsayesJeffrey J Brown
Oct 22, 2008·Cases Journal·Basilios PapaziogasKonstantinos Atmatzidis
Jun 22, 2012·World Journal of Gastroenterology : WJG·Mao-Lin YanYing Lin
Sep 15, 2012·Clinical Endoscopy·Mi-Jeong LeeDo Sang Lee
Dec 3, 2014·Internal Medicine·Tatsuaki SumiyoshiSojiro Morita
Jun 27, 2015·Journal of Gastrointestinal and Liver Diseases : JGLD·Jan UlrychDavid Zogala
Mar 14, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Maryam RezvaniAkram M Shaaban

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Citations

Nov 21, 2020·International Journal of Surgery Case Reports·Bruno Gadelha Bezerra SilvaAndré Átila Alencar Barros

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Methods Mentioned

BETA
biopsy

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