PMID: 7062088Feb 1, 1982Paper

Heterotopic regeneration of peripheral nerve fibres into the subarachnoid space

Journal of Neurocytology
C S RaineD E McFarlin


Within the spinal cord meninges of SJL/J mice afflicted with chronic relapsing experimental allergic encephalomyelitis for up to seven months postinoculation, networks of aberrant regenerated nerve fibres myelinated by Schwann cells have been observed. These P.N.S. elements are believed to have been derived from incoming sensory fibres from the spinal nerve roots which had been interrupted during acute stages of the disease. This phenomenon might also have been related to the occurrence of marked nerve fibre loss and gliosis within superficial tracts in the spinal cord. P.N.S. elements within the subarachnoid space were first apparent six weeks postinoculation, and were distributed around the entire spinal cord and tended to be more concentrated around meningeal blood vessels. Schwann cells associated with these fibres frequently contained centrioles and cilia and daughter Schwann cells apparently arose from parent cells already committed to axons.


Nov 1, 1979·Annals of Neurology·D BoghenM Aube
Oct 1, 1978·Journal of Neurocytology·C S RaineS H Stone
May 1, 1975·Journal of Neuropathology and Experimental Neurology·D H SnyderC S Raine
Nov 1, 1975·Journal of Neuropathology and Experimental Neurology·I Feigin, G N Budzilovich
Oct 1, 1973·Archives of Neurology·N R GhatakH M Zimmerman
Jan 1, 1974·The Journal of Comparative Neurology·R E CoggeshallW D Willis
Nov 1, 1980·Neuropathology and Applied Neurobiology·W F Blakemore

❮ Previous
Next ❯


Jan 1, 1993·Brain Research Bulletin·S A GilmoreT J Sims
Feb 1, 1995·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·B S Kaplan

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.