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Hexamethylmelamine: pharmacology and mechanism of action

Cancer Treatment Reviews

Mar 1, 1991

Matthew M Ames

PMID: 1904306

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Abstract

Several conclusions can be drawn from a review of HMM preclinical and clinical pharmacology data. The drug is extensively metabolized by animals and by man. The drug is well absorbed following oral administration to animals, but oral bioavailability is low due to first pass metabolism. ...read more

Mentioned in this Paper

Dye Exclusion Assays, Antitumor
Drug Evaluation
Drug Kinetics
Activation, Metabolic
Hexinawas
Metazoa
Metabolic Aspects
Metabolite
Metabolic Process, Cellular
Urinary Tract
Paper Details
References
  • References17
  • Citations5
12

Hexamethylmelamine: pharmacology and mechanism of action

Cancer Treatment Reviews

Mar 1, 1991

Matthew M Ames

PMID: 1904306

DOI:

Abstract

Several conclusions can be drawn from a review of HMM preclinical and clinical pharmacology data. The drug is extensively metabolized by animals and by man. The drug is well absorbed following oral administration to animals, but oral bioavailability is low due to first pass metabolism. ...read more

Mentioned in this Paper

Dye Exclusion Assays, Antitumor
Drug Evaluation
Drug Kinetics
Activation, Metabolic
Hexinawas

Related Papers

Paper Details
References
  • References17
  • Citations5
12

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