PMID: 5917551Aug 26, 1966

Hexose-6-phosphate dehydrogenase found in human liver

Science
S OhnoE Beutler

Abstract

Starch-gel electrophoresis of extracts of human liver revealed the presence of a new hexose-6-phosphate dehydrogenase that was slower-moving at pH 8.6 than the sex-linked glucose-6-phosphate dehydrogenase. When the gel plate was stained, galactose-6-phos phate being used as a substrate, this enzyme band stained intensely, but the sex-linked glucose-6-phosphate dehydro genase failed to stain. This new human enzyme may well be homologous with the autosomally inherited glucose-6-phosphate dehydrogenase of the deer mouse (Peromyscus maniculatus), re ported by Shaw and Barto.

Citations

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Related Concepts

Alcohol Oxidoreductases
Bos indicus
Electrophoresis
Glucosephosphate Dehydrogenase
Liver

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