PMID: 5917551Aug 26, 1966

Hexose-6-phosphate dehydrogenase found in human liver

S OhnoE Beutler


Starch-gel electrophoresis of extracts of human liver revealed the presence of a new hexose-6-phosphate dehydrogenase that was slower-moving at pH 8.6 than the sex-linked glucose-6-phosphate dehydrogenase. When the gel plate was stained, galactose-6-phos phate being used as a substrate, this enzyme band stained intensely, but the sex-linked glucose-6-phosphate dehydro genase failed to stain. This new human enzyme may well be homologous with the autosomally inherited glucose-6-phosphate dehydrogenase of the deer mouse (Peromyscus maniculatus), re ported by Shaw and Barto.


Apr 1, 1976·Biochemical Genetics·S D Cederbaum, A Yoshida
Dec 1, 1971·Biochemical Genetics·J J Stegeman, E Goldberg
Mar 1, 1987·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·P G West, W W Baker
Jan 1, 1976·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·Y Mochizuki, S H Hori
Jan 1, 1977·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·R H Broyles, C F Strittmatter
Jan 1, 1983·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·Y Mochizuki
Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·W J Berg, D G Buth
Oct 1, 1994·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·M A TranulisB Borrebaek
May 1, 1968·Annals of Human Genetics·R H Bigley, R D Koler
Aug 1, 1972·Biological Reviews of the Cambridge Philosophical Society·C J Masters, R S Holmes
Jun 14, 1968·Annals of the New York Academy of Sciences·H N Kirkman, J E Hanna
Jan 1, 1976·Journal of Cellular Physiology·W R PendergrassP Bornstein
Jun 14, 1968·Annals of the New York Academy of Sciences·C R Shaw, A L Koen
Jan 24, 1977·Biochimica Et Biophysica Acta·S H Hori, T Takahashi
Apr 14, 1971·Biochimica Et Biophysica Acta·K Taketa, A Watanabe
Feb 27, 1981·Biochemical and Biophysical Research Communications·Y Hino, S Minakami
Dec 11, 1974·Biochemical and Biophysical Research Communications·S H Hori, T Takahashi
May 1, 1967·Metabolism: Clinical and Experimental·D Y Hsia
Nov 1, 1970·Archives of Biochemistry and Biophysics·B MandulaE Beutler
Jan 30, 1981·Biochemical and Biophysical Research Communications·C Bublitz
Apr 21, 1975·Biochemical and Biophysical Research Communications·R P Erickson
May 13, 2010·Drug Metabolism and Pharmacokinetics·Yuji IshiiHideyuki Yamada
Jul 2, 1971·Nature·R F MurrayB Payne
Mar 1, 1983·Jinrui idengaku zasshi. The Japanese journal of human genetics·Y KeraS Komura

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