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High and Low Molecular Weight Hyaluronic Acid Differentially Influences Oxylipins Synthesis in Course of Neuroinflammation

International Journal of Molecular Sciences

Aug 9, 2019

Dmitry V ChistyakovMarina G Sergeeva

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Abstract

Hyaluronic acid (HA), a major glycosaminoglycan of the extracellular matrix, has cell signaling functions that are dependent on its molecular weight. Anti-inflammatory effects for high-molecular-weight (HMW) HA and pro-inflammatory effects for low-molecular-weight (LMW) HA effects were ...read more

Mentioned in this Paper

Arachidonic Acid
Astrocytes
Down-Regulation
Encephalitis
Extracellular Matrix
Fatty Acids
Glycosaminoglycans
Hyaluronic Acid
Inflammation
Interleukin-6
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High and Low Molecular Weight Hyaluronic Acid Differentially Influences Oxylipins Synthesis in Course of Neuroinflammation

International Journal of Molecular Sciences

Aug 9, 2019

Dmitry V ChistyakovMarina G Sergeeva

PMID: 31405034

DOI: 10.3390/ijms20163894

Abstract

Hyaluronic acid (HA), a major glycosaminoglycan of the extracellular matrix, has cell signaling functions that are dependent on its molecular weight. Anti-inflammatory effects for high-molecular-weight (HMW) HA and pro-inflammatory effects for low-molecular-weight (LMW) HA effects were ...read more

Mentioned in this Paper

Arachidonic Acid
Astrocytes
Down-Regulation
Encephalitis
Extracellular Matrix

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