High birth weight and risk of multiple sclerosis: A multicentre study in Argentina.

Multiple Sclerosis and Related Disorders
Geraldine G LueticJuan I Rojas

Abstract

Multiple sclerosis (MS) is now recognized as a multifactorial disease in which genetic and environmental factors intervene. Considerable efforts have been made to identify external risk factors present in childhood, adolescence and youth, though only a few perinatal risk factors have been positively associated with MS. Previously, we found an association between high birth weight and MS in male patients in a small study in Argentina. The present research was designed to further assess the association between high birth weight and MS in a larger sample of patients, using an extensive and validated general population database as control. We present an analytical observational, multicentre, population-based, and case-control study. A total of 637 patients (cases) with confirmed MS diagnosis attending five MS specialized centres in Argentina were included. Birth weight (BW) data was recalled by the patient's mother, which is a validated approach. A two-way comparison was performed. First, we used the standard categories of high, adequate and low BW in grams. Then, we applied the weight percentile distribution to provide reproducible results for further research. For a proper assessment and comparison of variables, we adopted the gu...Continue Reading

References

Jan 1, 1991·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·D E PhillipsJ E Rydquist
Aug 1, 1987·British Journal of Obstetrics and Gynaecology·D S SeidmanR Gale
Jan 1, 1997·Annual Review of Genetics·M S Bartolomei, S M Tilghman
Feb 11, 1998·American Journal of Epidemiology·M SandersonD E Moore
Mar 29, 2001·Physiological Reviews·N Baumann, D Pham-Dinh
May 17, 2003·BMJ : British Medical Journal·Lennart T H JacobssonWilliam C Knowler
Sep 7, 2004·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·D J P Barker
Dec 9, 2004·BMJ : British Medical Journal·Cristen J WillerUNKNOWN Canadian Collaborative Study Group
Sep 20, 2005·Lancet Neurology·A Dessa SadovnickUNKNOWN Canadian Collaborative Study Group
Sep 21, 2006·International Journal of Epidemiology·Lucy J GriffithsTim J Cole
Apr 6, 2007·Nutrition·María C OchoaUNKNOWN GENOI Members
Jul 25, 2007·Proceedings of the National Academy of Sciences of the United States of America·Peter D GluckmanMark A Hanson
May 20, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·A R A Adegboye, Bl Heitmann
Aug 5, 2008·BMC Neurology·Sreeram V RamagopalanUNKNOWN Canadian Collaborative Study Group
Sep 12, 2008·Neuroepidemiology·Sreeram V RamagopalanA Dessa Sadovnick
Apr 1, 2009·Epidemiology·Hannah GardenerAlberto Ascherio
Nov 11, 2009·Neurology·Kassandra L MungerAlberto Ascherio
Jan 7, 2010·Neuroepidemiology·Sreeram V RamagopalanA Dessa Sadovnick
Mar 2, 2010·Expert Review of Neurotherapeutics·Klaus Lauer
Jul 9, 2010·Lancet Neurology·Sreeram V RamagopalanGavin Giovannoni
Mar 10, 2011·Annals of Neurology·Chris H PolmanJerry S Wolinsky
Feb 14, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Anna K HedströmLars Alfredsson
May 2, 2012·Current Opinion in Neurology·Kelly C SimonAlberto Ascherio
Sep 7, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Silja ConradiBerit Rosche
Oct 23, 2013·European Journal of Epidemiology·Anna Karin HedströmLars Alfredsson
Dec 7, 2013·Expert Review of Neurotherapeutics·Alberto Ascherio
May 30, 2014·Neurology·Fred D LublinChris H Polman
Dec 30, 2014·Biochimica Et Biophysica Acta·Sebastian SchmittMikael Simons
Mar 1, 2015·Biochimica Et Biophysica Acta·Gesine Saher, Sina Kristin Stumpf
May 14, 2016·Pediatric Obesity·E A MitchellUNKNOWN ISAAC Phase Three Study Group
Oct 21, 2016·Journal of Endocrinological Investigation·C ParrinoL Frittitta
Jun 29, 2016·PLoS Medicine·Lauren E MokryJ Brent Richards
Sep 21, 2016·Multiple Sclerosis and Related Disorders·E CristianoJ I Rojas
Apr 22, 2017·Multiple Sclerosis and Related Disorders·Alexander GoldacreMichael Goldacre
Dec 26, 2017·Lancet Neurology·Alan J ThompsonJeffrey A Cohen
Oct 10, 2018·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·R Dobson, G Giovannoni

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Human Biology : the Official Journal of the Human Biology Council
Zaneta M ThayerChristopher W Kuzawa
BJOG : an International Journal of Obstetrics and Gynaecology
A R A Adegboye, Bl Heitmann
© 2021 Meta ULC. All rights reserved