High burden of metabolic comorbidities in a citywide cohort of HIV outpatients: evolving health care needs of people aging with HIV in Washington, DC

HIV Medicine
M E LevyDC Cohort Executive Committee

Abstract

With the increasing impact of cardiovascular disease among populations aging with HIV, contemporary prevalence estimates for predisposing metabolic comorbidities will be important for guiding the provision of relevant lifestyle and pharmacological interventions. We estimated the citywide prevalence of hypertension, type 2 diabetes, dyslipidaemia, and obesity; examined differences by demographic subgroups; and assessed clinical correlates. Utilizing an electronic medical record (EMR) database from the DC Cohort study - a multicentre prospective cohort study of HIV-infected outpatients - we assessed the period prevalence of metabolic comorbidities between 2011 and 2015 using composite definitions that incorporated diagnoses, pharmacy records, and clinical/laboratory results. Of 7018 adult patients (median age 50 years; 77% black), 50% [95% confidence interval (CI) 49-51] had hypertension, 13% (95% CI: 12-14) had diabetes, 48% (95% CI: 47-49) had dyslipidaemia, and 35% (95% CI: 34-36) had obesity. Hypertension was more prevalent among black patients, diabetes and obesity were more prevalent among female and black patients, dyslipidaemia was more prevalent among male and white patients, and comorbidities were more prevalent among o...Continue Reading

References

Sep 21, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert C KaplanStephen J Gange
Jan 15, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph L GouletAmy C Justice
Jun 12, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Magdalena E SobieszczykUNKNOWN Women's Interagency HIV Study
Dec 17, 2008·Atherosclerosis·Ugo OlivieroLuigi Saccà
May 16, 2009·AIDS·Adeel A ButtUNKNOWN Veterans Aging Cohort Study
Jun 27, 2009·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Kristina CrothersAmy C Justice
Dec 17, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Matthew S FreibergUNKNOWN VACS Project Team
Feb 9, 2010·HIV Medicine·J V Lazarus, K K Nielsen
Feb 19, 2010·Current HIV Research·Paolo BonfantiElena Ricci
Apr 29, 2010·Current HIV/AIDS Reports·Amy C Justice
Aug 21, 2010·American Journal of Public Health·Alan R LifsonUNKNOWN INSIGHT SMART Study Group
Mar 2, 2011·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Carolyn Chu, Peter A Selwyn
Apr 1, 2011·European Journal of Preventive Cardiology·Nico ReinschUNKNOWN German Competence Network for HIV/AIDS
Jun 15, 2011·Best Practice & Research. Clinical Endocrinology & Metabolism·Michael P Dubé, Joseph J Cadden
Oct 15, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Giovanni GuaraldiFrank Palella
Nov 18, 2011·AIDS·Jacqueline CapeauUNKNOWN ANRS CO8 APROCO-COPILOTE Cohort Study Group
Dec 1, 2011·Sexual Health·Richard J HavlikStephen E Karpiak
Apr 27, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kaku A ArmahMatthew Freiberg
Jan 12, 2013·AIDS Patient Care and STDs·Alan T Rodriguez-PenneyUNKNOWN HIV Neurobehavioral Research Program HNRP Group
Jan 24, 2013·The Journal of Clinical Hypertension·Ingjerd W MannerIngrid Os
Jan 26, 2013·Preventing Chronic Disease·Kenneth A LichtensteinUNKNOWN HOPS Investigators
Jun 7, 2013·Drugs & Aging·E Jennifer EdelmanAmy C Justice
Jul 24, 2013·The Journal of the Association of Nurses in AIDS Care : JANAC·Gyasi Moscou-JacksonMichelle DiGiacomo
Oct 25, 2013·Lancet·Steven G DeeksDiane V Havlir
Oct 26, 2013·The Lancet Infectious Diseases·Jordan E Lake, Judith S Currier
Dec 18, 2013·AIDS Research and Therapy·Adelzon A PaulaAntonio G Pacheco
Feb 14, 2014·European Journal of Endocrinology·Suman Srinivasa, Steven K Grinspoon
Mar 29, 2014·Journal of the International Association of Providers of AIDS Care·Janice B SchwartzOluwatoyin M Adeyemi
Apr 16, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Merle MyersonHeejung Bang
Mar 13, 2015·The Journal of Infectious Diseases·Alison G AbrahamLisa P Jacobson
Apr 12, 2015·Neurology·Jason J SicoUNKNOWN Veterans Aging Cohort Study
May 12, 2015·HIV Medicine·J R KoetheUNKNOWN North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD)
Sep 10, 2015·AIDS Research and Human Retroviruses·John R KoetheUNKNOWN North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD)
Dec 8, 2015·The American Journal of Cardiology·Matthew J FeinsteinDonald M Lloyd-Jones
Oct 19, 2016·AIDS·Maryam ShahmaneshUNKNOWN EuroSIDA in EuroCOORD

❮ Previous
Next ❯

Citations

Oct 19, 2017·Current HIV/AIDS Reports·Jordan E Lake
Aug 23, 2018·AIDS·Annegret Pelchen-MatthewsUNKNOWN EuroSIDA study
Oct 26, 2018·AIDS Research and Human Retroviruses·Matthew E LevyUNKNOWN DC Cohort Executive Committee
Nov 27, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Julie A AkeUNKNOWN African Cohort Study Team
Mar 10, 2020·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Hemil GonzalezJennillee Wallace
Jun 17, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Lindsey Powers HappUNKNOWN DC Cohort Executive Committee
Aug 20, 2020·AIDS Care·David E WallaceUNKNOWN DC Cohort Executive Committee
Sep 21, 2018·Frontiers in Endocrinology·Marcelo N PedroMario J A Saad
Jul 23, 2020·Revista latino-americana de enfermagem·Priscila Silva PontesRenata Karina Reis
Apr 5, 2019·AIDS·Sascha AlbrechtUNKNOWN KIULARCO Study Group
Sep 26, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Veeral H AjmeraRohit Loomba
Jun 19, 2021·AIDS Research and Human Retroviruses·Norberto Quiles, Alexis Ortiz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Aging

This feed focuses on cellular aging with emphasis on mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Aging-Associated Metabolic Disorders

Age is associated with many metabolic disorders including cardiovascular diseases, type 2 diabetes, stroke and heart disease. The mediators in aging process have been suggested to play a part in the cellular processes responsible for these metabolic disorders. Here is the latest research on aging-associated metabolic disorders.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.

Cell Aging (Keystone)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.