High capacity for extracellular acid-base regulation in the air-breathing fish Pangasianodon hypophthalmus

The Journal of Experimental Biology
Christian DamsgaardM Bayley

Abstract

The evolution of accessory air-breathing structures is typically associated with reduction of the gills, although branchial ion transport remains pivotal for acid-base and ion regulation. Therefore, air-breathing fishes are believed to have a low capacity for extracellular pH regulation during a respiratory acidosis. In the present study, we investigated acid-base regulation during hypercapnia in the air-breathing fish Pangasianodon hypophthalmus in normoxic and hypoxic water at 28-30°C. Contrary to previous studies, we show that this air-breathing fish has a pronounced ability to regulate extracellular pH (pHe) during hypercapnia, with complete metabolic compensation of pHe within 72 h of exposure to hypoxic hypercapnia with CO2 levels above 34 mmHg. The high capacity for pHe regulation relies on a pronounced ability to increase levels of HCO3(-) in the plasma. Our study illustrates the diversity in the physiology of air-breathing fishes, such that generalizations across phylogenies may be difficult.

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Citations

Dec 15, 2015·Physiological and Biochemical Zoology : PBZ·William JoyceTobias Wang
Jul 28, 2016·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Graham R ScottAdalberto L Val
Oct 28, 2016·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Le My PhuongMark Bayley
Mar 1, 2018·The Journal of Experimental Biology·Phan Vinh ThinhTobias Wang
Mar 5, 2018·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Dang Diem TuongWilliam K Milsom
Dec 13, 2018·Physiology·Mark BayleyTobias Wang
Oct 29, 2018·Fish Physiology and Biochemistry·Cristiano Campos MattioliRonald Kennedy Luz
Nov 11, 2017·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Christian DamsgaardTobias Wang
Oct 21, 2019·Acta Physiologica·Christian DamsgaardPatricia A Wright
Sep 26, 2019·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Dang Diem TuongWilliam K Milsom
Mar 5, 2020·The Journal of Experimental Biology·R B ShartauC J Brauner
Aug 20, 2019·Fish Physiology and Biochemistry·Cristiano Campos MattioliRonald Kennedy Luz
Jan 1, 2018·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Alexander M CliffordGreg G Goss
Jul 6, 2019·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Vinicius Araújo ArmelinTobias Wang
Mar 28, 2021·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Rachael MorganWilliam K Milsom

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