High circulation of Hepatitis E virus in pigs and professionals exposed to pigs in Laos

Zoonoses and Public Health
Vilaysone KhounvisithMaude Pauly

Abstract

Epidemiological characteristics of hepatitis E Virus (HEV) differ due to the vast spatial heterogeneity in sanitation status, dietary habits and extent of exposure to animals. Although HEV infections are mostly asymptomatic, prognosis is poor for patients with compromised immune systems or pre-existing liver disease and during pregnancy. In developing countries, low hygienic standards and close human-animal interactions at farms and slaughterhouses likely favour zoonotic transmission of the virus. In this cross-sectional study from Lao People's Democratic Republic, anti-HEV IgG was detected by ELISA in 54.0% (136/252) of slaughter pigs, in 41.0% (57/139) of professionals exposed to pigs and in 18.1% of the nonrisk controls (38/210). We show that people occupationally exposed to pigs are at higher risk of infection (p < 0.001). In particular, contact to young piglets as compared to contact to the older slaughter pigs was a major risk factor (p = 0.011). Besides, consumption of bottled water significantly reduced the risk of infection (p = 0.018). In conclusion, we show that in Lao PDR, the high endemicity of HEV, the inadequate implementation of hygiene measures and the limited access to safe water jeopardize the health of profe...Continue Reading

References

Jul 1, 1991·Gastroenterologia Japonica·H ZhuangG M Wang
Jun 1, 1996·The American Journal of Tropical Medicine and Hygiene·A L CorwinK C Hyams
Jul 1, 1997·The American Journal of Tropical Medicine and Hygiene·A CorwinK C Hyams
Nov 3, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·K BounluA L Corwin
Dec 12, 2001·The Journal of Infectious Diseases·J DrobeniucH S Margolis
Aug 30, 2005·Journal of Virological Methods·Narayanan JothikumarVincent R Hill
Feb 21, 2006·Emerging Infectious Diseases·Tian-Cheng LiTatsuo Miyamura
Aug 22, 2006·Transactions of the Royal Society of Tropical Medicine and Hygiene·Stuart D BlacksellPaul N Newton
Feb 26, 2009·Emerging Infectious Diseases·Saskia A RutjesAna Maria de Roda Husman
May 19, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·Masaaki KitajimaShinichiro Ohgaki
Aug 14, 2009·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yibin ChangHui Zhuang
Apr 10, 2010·Transactions of the Royal Society of Tropical Medicine and Hygiene·Bounkong SyhavongPaul N Newton
Jul 6, 2010·Applied and Environmental Microbiology·Giuseppina La RosaMichele Muscillo
Aug 11, 2010·The Journal of Infectious Diseases·Philippe ColsonRené Gerolami
May 10, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·James V ConlanStuart D Blacksell
Jul 21, 2011·Medical Microbiology and Immunology·Andi KrumbholzRoland Zell
Aug 2, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Andrej SteyerMario Poljak
Sep 21, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Rakesh Aggarwal, Shahid Jameel
Sep 24, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D ParasharV A Arankalle
Apr 28, 2012·Gastroenterology·Heiner WedemeyerMichael P Manns
May 3, 2012·Lancet·Nassim KamarHarry R Dalton
Jun 6, 2012·The American Journal of Tropical Medicine and Hygiene·James V ConlanStuart D Blacksell
Nov 14, 2012·The Journal of Infectious Diseases·Jürgen J WenzelWolfgang Jilg
Jun 25, 2013·Foodborne Pathogens and Disease·Soawapak HinjoyPrapas Patchanee
Jan 8, 2014·Clinical Microbiology Reviews·Nassim KamarJacques Izopet
Jan 8, 2014·Clinical Microbiology Reviews·Lisa J KrainAlain B Labrique
Mar 5, 2014·The American Journal of Tropical Medicine and Hygiene·Tian-Cheng LiKoji Ishii
May 24, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Emily S GurleyStephen P Luby
Sep 13, 2014·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Maribel G Martínez WassafViviana E Ré
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Oct 24, 2014·Emerging Infectious Diseases·Christophe RenouNicole Pavio
Jun 28, 2015·Food and Environmental Virology·M IaconelliGiuseppina La Rosa
Dec 15, 2015·Journal of Clinical Microbiology·Heléne NorderMartin Lagging
Feb 5, 2016·EBioMedicine·Nghiem Xuan HoanThirumalaisamy P Velavan
Sep 2, 2016·Food and Environmental Virology·Duangnapa IntharasongkrohYong Poovorawan

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Citations

Dec 12, 2019·Current Environmental Health Reports·Caroline Dignard, Jessica H Leibler

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