High CO2 and silicate limitation synergistically increase the toxicity of Pseudo-nitzschia fraudulenta.

PloS One
Avery O TattersDavid A Hutchins

Abstract

Anthropogenic CO(2) is progressively acidifying the ocean, but the responses of harmful algal bloom species that produce toxins that can bioaccumulate remain virtually unknown. The neurotoxin domoic acid is produced by the globally-distributed diatom genus Pseudo-nitzschia. This toxin is responsible for amnesic shellfish poisoning, which can result in illness or death in humans and regularly causes mass mortalities of marine mammals and birds. Domoic acid production by Pseudo-nitzschia cells is known to be regulated by nutrient availability, but potential interactions with increasing seawater CO(2) concentrations are poorly understood. Here we present experiments measuring domoic acid production by acclimatized cultures of Pseudo-nitzschia fraudulenta that demonstrate a strong synergism between projected future CO(2) levels (765 ppm) and silicate-limited growth, which greatly increases cellular toxicity relative to growth under modern atmospheric (360 ppm) or pre-industrial (200 ppm) CO(2) conditions. Cellular Si:C ratios decrease with increasing CO(2), in a trend opposite to that seen for domoic acid production. The coastal California upwelling system where this species was isolated currently exhibits rapidly increasing levels...Continue Reading

References

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Citations

Aug 28, 2013·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Avery O TattersDavid A Hutchins
Sep 3, 2013·Environmental Pollution·Khan M G MostofaHiroshi Ogawa
Dec 23, 2015·Journal of the Marine Biological Association of the United Kingdom·Elisa BerdaletHenrik Enevoldsen
Aug 11, 2017·Scientific Reports·Craig S Young, Christopher J Gobler
Jul 1, 2020·International Journal of Environmental Research and Public Health·Laura J FalkenbergSam Dupont
Apr 1, 2014·Functional Plant Biology : FPB·Kunshan Gao, Douglas A Campbell
May 26, 2017·Nature Microbiology·David A Hutchins, Feixue Fu
Feb 15, 2020·Harmful Algae·Andrew W Griffith, Christopher J Gobler
Jan 23, 2021·The Science of the Total Environment·Andrea E BrookfieldGrace Wilkinson
Oct 5, 2019·Harmful Algae·Suzanna ClarkDavid W Townsend
Nov 14, 2018·Harmful Algae·Stephen S BatesChui Pin Leaw
Aug 17, 2021·Conservation Physiology·Maximilian Berthold, Douglas A Campbell
Sep 7, 2020·Toxicon : Official Journal of the International Society on Toxinology·Goran GajskiBojana Žegura

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Software Mentioned

CO 2 SYS
EZ START

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