High concentration of residual aluminum oxide on titanium surface inhibits extracellular matrix mineralization

Journal of Biomedical Materials Research. Part a
A CanabarroR G Fischer

Abstract

In the present study we characterized titanium (Ti) surfaces submitted to different treatments and evaluated the response of osteoblasts derived from human alveolar bone to these surfaces. Five different surfaces were evaluated: ground (G), ground and chemical etched (G1-HF for 60 s), sand blasted (SB-Al(2)O(3) particles 65 mum), sand blasted and chemical etched (SLA1-HF for 60 s and SLA2-HF for 13 s). Surface morphology was evaluated under SEM and roughness parameters by contact scanning instrument. The presence of Al(2)O(3) was detected by EDS and the amount calculated by digital analyses. Osteoblasts were cultured on these surfaces and it was evaluated: cell adhesion, proliferation, and viability, alkaline phosphatase activity, total protein content, and matrix mineralization formation. Physical and chemical treatments produced very different surface morphologies. Al(2)O(3) residues were detected on SB and SLA2 surfaces. Only matrix mineralization formation was affected by different surface treatments, being increased on rough surface (SLA1) and reduced on surface with high amount of Al(2)O(3) residues (SB). On the basis of these findings, it is possible to conclude that high concentration of residual Al(2)O(3) negatively in...Continue Reading

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Citations

Dec 2, 2010·Implant Dentistry·Luigi F RodellaRita Rezzani
May 28, 2015·Journal of Biomedical Materials Research. Part a·Niall LoganPeter Brett
Oct 29, 2015·Journal of Biomaterials Applications·Luiz F GilPaulo G Coelho
Jul 23, 2016·The Journal of Contemporary Dental Practice·Mogammad T Peck, Bruno R Chrcanovic
May 14, 2021·Physiological Research·M Lukaszewska-KuskaB Dorocka-Bobkowska

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